Fetal pathology in second-trimester miscarriages

József Gábor Joó, A. Beke, Eniko Berkes, Z. Papp, J. Rigó, C. Papp

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective: We aimed to analyze, based upon autopsy, the main characteristics of miscarriages in the second trimester. Methods: We have processed the results of fetopathological investigations of 544 aborted fetuses resulting from 486 second-trimester miscarriages. Results: Malformation could be identified in 13.05% of all cases. In almost one third of the patients there was a positive history. In the cases having a malformation, expressed dominance of male fetuses could be observed. Among the fetopathologically identified malformations, 49 were isolated. The most common was the single umbilical artery (22.4%). In 1.3% of the cases a chromosome aberration was verified. Conclusion: Miscarriage in pregnancies complicated by a malformation occurs approximately 3 weeks earlier than in cases without a confirmed malformation. There is practically no difference between affected and unaffected miscarriages as far as the cumulative ratio of positive history is concerned. A single umbilical artery alone predisposes to miscarriage, while in association with other malformations it may result from chromosome aberration.

Original languageEnglish
Pages (from-to)186-191
Number of pages6
JournalFetal Diagnosis and Therapy
Volume25
Issue number2
DOIs
Publication statusPublished - Aug 2009

Fingerprint

Second Pregnancy Trimester
Spontaneous Abortion
Pathology
Single Umbilical Artery
Chromosome Aberrations
History
Aborted Fetus
Autopsy
Fetus
Pregnancy

Keywords

  • Associated malformations
  • Gender distribution
  • Miscarriage
  • Positive history
  • Single umbilical artery

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Pediatrics, Perinatology, and Child Health
  • Embryology
  • Radiology Nuclear Medicine and imaging

Cite this

Fetal pathology in second-trimester miscarriages. / Joó, József Gábor; Beke, A.; Berkes, Eniko; Papp, Z.; Rigó, J.; Papp, C.

In: Fetal Diagnosis and Therapy, Vol. 25, No. 2, 08.2009, p. 186-191.

Research output: Contribution to journalArticle

Joó, József Gábor ; Beke, A. ; Berkes, Eniko ; Papp, Z. ; Rigó, J. ; Papp, C. / Fetal pathology in second-trimester miscarriages. In: Fetal Diagnosis and Therapy. 2009 ; Vol. 25, No. 2. pp. 186-191.
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