Feminizáló genitoplastica felnottkorban, congenitalis adrenalis hyperplasia (CAH) miatt

Translated title of the contribution: Feminizing genitoplasty for congenital adrenal hyperplasia (CAH) in adult

János Dancsó, Zoltán Jenovári, Jeno Egyed, Péter Balázs, Zsuzsanna Kincses, I. Szabolcs, V. Fülöp

Research output: Contribution to journalArticle

Abstract

Adrenogenital syndrome or congenital adrenal hyperplasia is a genetically determined ensyme deficiency of the 21-hydroxylase that is a key ensyme in the synthesis of cortisol from cholesterol. 75% of patients are salt-wasting. The average incidence is 1 to 15 000 live birth. The androgene overproduction causes clitoral hyperplasia, persistent common urogenital sinus, vaginal hypoplasia and other intersexual abnormalities. In the childhood and puberty it may lead to serious psychosexual developmental abnormalities. There is an agreement, that the surgical correction should be done as early as 3-4 weeks or 1-2 year after birth to avoid the unnecessary psychosexual strain. It helps to develop an early gender identity. We operated a 29 year old lady with CAH and excessive clitoral hypertrophy. We used successfully the same one step operative technique as in infants, with small modifications. We demonstrated the intervention with photos. The postoperative period was without any complication. 6 month later the clitoral sensation partially returned.

Original languageHungarian
Pages (from-to)401-406
Number of pages6
JournalMagyar Noorvosok Lapja
Volume68
Issue number6
Publication statusPublished - 2005

Fingerprint

Congenital Adrenal Hyperplasia
Adrenogenital Syndrome
Live Birth
Puberty
Postoperative Period
Hypertrophy
Hyperplasia
Hydrocortisone
Salts
Cholesterol
Parturition
Incidence
Congenital adrenal hyperplasia due to 21 hydroxylase deficiency

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Feminizáló genitoplastica felnottkorban, congenitalis adrenalis hyperplasia (CAH) miatt. / Dancsó, János; Jenovári, Zoltán; Egyed, Jeno; Balázs, Péter; Kincses, Zsuzsanna; Szabolcs, I.; Fülöp, V.

In: Magyar Noorvosok Lapja, Vol. 68, No. 6, 2005, p. 401-406.

Research output: Contribution to journalArticle

Dancsó, J, Jenovári, Z, Egyed, J, Balázs, P, Kincses, Z, Szabolcs, I & Fülöp, V 2005, 'Feminizáló genitoplastica felnottkorban, congenitalis adrenalis hyperplasia (CAH) miatt', Magyar Noorvosok Lapja, vol. 68, no. 6, pp. 401-406.
Dancsó J, Jenovári Z, Egyed J, Balázs P, Kincses Z, Szabolcs I et al. Feminizáló genitoplastica felnottkorban, congenitalis adrenalis hyperplasia (CAH) miatt. Magyar Noorvosok Lapja. 2005;68(6):401-406.
Dancsó, János ; Jenovári, Zoltán ; Egyed, Jeno ; Balázs, Péter ; Kincses, Zsuzsanna ; Szabolcs, I. ; Fülöp, V. / Feminizáló genitoplastica felnottkorban, congenitalis adrenalis hyperplasia (CAH) miatt. In: Magyar Noorvosok Lapja. 2005 ; Vol. 68, No. 6. pp. 401-406.
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