Female Gender and Differences in Outcome after Isolated Coronary Artery Bypass Graft Surgery: Does Age Play a Role?

Rawa Arif, Mina Farag, Victor Gertner, G. Szabó, Alexander Weymann, Gabor Veres, Arjang Ruhparwar, Raffi Bekeredjian, Tom Bruckner, Matthias Karck, Klaus Kallenbach, Carsten J. Beller

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Introduction Female gender is a known risk factor for early and late mortality after coronary artery bypass graft surgery (CABG). Higher age of women at operation may influence outcome, since age per se is also an important risk factor. The purpose of our study was to analyze possible gender differences in outcome after isolated CABG in different age groups to delineate the impact of female gender and age. Methods All patients over 60 years of age undergoing isolated CABG at our department during 2001 and 2011 were included and categorized by age into sexagenarians (2266, 16.6% women), septuagenarians (2332, 25.4% women) and octogenarians (374, 32% women) and assessed by gender for 30-day and 180-day mortality. Results Thirty-day mortality was significantly higher in women only amongst septuagenarians (7.1 vs. 4.7%, p = 0.033). Same differences apply for 180-day mortality (12.3 vs. 8.2%, p = 0.033) and estimated one-year survival (81.6 ± 4.2 vs. 86.9 ± 2.2%, p = 0.001). Predictive factors for 30-day mortality of septuagenarian were logistic EuroSCORE (ES) (p = 0.003), perioperative myocardial infarction (MI) (p

Original languageEnglish
Article numbere0145371
JournalPLoS One
Volume11
Issue number2
DOIs
Publication statusPublished - Feb 1 2016

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coronary vessels
Grafts
Coronary Artery Bypass
Surgery
surgery
Transplants
Mortality
gender
Logistics
risk factors
myocardial infarction
gender differences
Age Groups
Myocardial Infarction
Survival

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Female Gender and Differences in Outcome after Isolated Coronary Artery Bypass Graft Surgery : Does Age Play a Role? / Arif, Rawa; Farag, Mina; Gertner, Victor; Szabó, G.; Weymann, Alexander; Veres, Gabor; Ruhparwar, Arjang; Bekeredjian, Raffi; Bruckner, Tom; Karck, Matthias; Kallenbach, Klaus; Beller, Carsten J.

In: PLoS One, Vol. 11, No. 2, e0145371, 01.02.2016.

Research output: Contribution to journalArticle

Arif, R, Farag, M, Gertner, V, Szabó, G, Weymann, A, Veres, G, Ruhparwar, A, Bekeredjian, R, Bruckner, T, Karck, M, Kallenbach, K & Beller, CJ 2016, 'Female Gender and Differences in Outcome after Isolated Coronary Artery Bypass Graft Surgery: Does Age Play a Role?', PLoS One, vol. 11, no. 2, e0145371. https://doi.org/10.1371/journal.pone.0145371
Arif, Rawa ; Farag, Mina ; Gertner, Victor ; Szabó, G. ; Weymann, Alexander ; Veres, Gabor ; Ruhparwar, Arjang ; Bekeredjian, Raffi ; Bruckner, Tom ; Karck, Matthias ; Kallenbach, Klaus ; Beller, Carsten J. / Female Gender and Differences in Outcome after Isolated Coronary Artery Bypass Graft Surgery : Does Age Play a Role?. In: PLoS One. 2016 ; Vol. 11, No. 2.
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