Fasting hypometabolism and thermoregulation in cold-adapted rats

E. Pétervári, M. Balaskó, Z. Szelényi, Z. Hummel, M. Székely

Research output: Contribution to journalArticle

8 Citations (Scopus)


(1) Cold-adapted rats, upon acute cold-exposure, exhibit overshoot increase in metabolic rate (MR) and paradoxical rise in core temperature (Tc). (2) Fasting causes suppression of resting (daytime) but not nocturnal MR and Tc. (3) In fasting rats, acute cold-exposure evokes relatively greater overshoot MR- and Tc-rises than in control rats, while central prostaglandin E induces relatively greater elevations in MR and Tc. (4) Re-feeding quickly reverses fasting-induced MR- and Tc-suppression, earlier than body weight is normalized. (5) The metabolic suppression originating from gastrointestinal signals can be overruled by opposite abdominal information (feeding) or by thermoregulatory information (cold signals).

Original languageEnglish
Pages (from-to)359-364
Number of pages6
JournalJournal of Thermal Biology
Issue number5
Publication statusPublished - Oct 1 2002


  • Body temperature
  • Cold-adaptation
  • Cold-exposure
  • Fasting
  • Hypometabolism
  • Prostaglandin E

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Agricultural and Biological Sciences(all)
  • Developmental Biology

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