Factorial design for the analysis of patient's quality of life in asthma

Ágnes Mészáros, R. Zelkó, Andrea Meskó, Zoltán Vincze

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Chronic diseases like asthma have a great impact on the everyday life of patients. Evaluation of a patient's quality of life informs us about how the patient is feeling and whether or not he or she is able to function physically, socially and emotionally. The objectives of this study were to assess the quality of life of asthmatic patients and to study the influence of age and disease severity, as independent variables, on the patient's quality of life. A 2-factor, 3-level face-centred central composite design was applied to construct a second-order polynomial model describing the effects of age and the severity on the quality of life. The second-order polynomial model was successfully applied to describe the effect of age and asthma severity with good correlation on the quality of life measured by either generic (Visual analogue scale) or disease specific (St George's Respiratory Questionnaire) instruments in the examined subjects. Our findings suggest quality of life may be used as a non-invasive patient-centred monitoring system as a guide for disease management if measured regularly.

Original languageEnglish
Pages (from-to)191-195
Number of pages5
JournalQuality of Life Research
Volume14
Issue number1
DOIs
Publication statusPublished - Feb 2005

Fingerprint

Asthma
Quality of Life
Statistical Models
Physiologic Monitoring
Disease Management
Visual Analog Scale
Emotions
Chronic Disease

Keywords

  • Asthma
  • Quality of life
  • Statistical experimental design

ASJC Scopus subject areas

  • Rehabilitation
  • Nursing(all)

Cite this

Factorial design for the analysis of patient's quality of life in asthma. / Mészáros, Ágnes; Zelkó, R.; Meskó, Andrea; Vincze, Zoltán.

In: Quality of Life Research, Vol. 14, No. 1, 02.2005, p. 191-195.

Research output: Contribution to journalArticle

Mészáros, Ágnes ; Zelkó, R. ; Meskó, Andrea ; Vincze, Zoltán. / Factorial design for the analysis of patient's quality of life in asthma. In: Quality of Life Research. 2005 ; Vol. 14, No. 1. pp. 191-195.
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