Facilitált revascularisatiós stratégia ST-elevációs myocardiuminfarctusban.

Translated title of the contribution: Facilitated revascularisation in myocardial infarction with ST-segment elevation

Mihály Józan-Jilling, I. Horváth, Ernó Kis, Imre Bodnár, Magdolna Baross, Arpád Zsigmond, Eva Kovács, L. Papp

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

AIMS: The authors performed urgent coronarography and revascularisation after administering a combined half dose of alteplase (tissue plazminogen activator) and eptifibatide (glycoprotein II/bIIIa receptor blocking agent) to patients suffering from acute coronary syndromes with persistent ST-segment elevation. METHODS: During the period between 01 April to 15 December, 2001. 20 patients (16 men and 4 women, mean age: 55.6 years) were treated. The localization of infarction on the basis of ST-segment elevation was: 9 cases inferior, 10 cases anterior and patient with left bundle branch block in 1 cases. The mean time between the infarct related angina and hospital admission was 158 (30-600) minutes. The combined medical therapy was initiated after 34 (15-150) minutes on the average admission, and 123 (71-210) minutes later the patients were in the catheter laboratory. RESULTS: Coronarography showed TIMI-0 flow in 4 cases, TIMI-2 flow in 3 cases and TIMI-3 flow in 13 cases. Acute percutan coronary intervention was done in 14 cases, aorto-coronary bypass surgery was performed in 4 cases (2 of them were emergency operations, the other 2 were done electively). Besides postpunctional haematomas, hemorrhagic complications in the form of haematemesis were observed in 2 cases, but there was no need for transfusion. The mean CK-MB release (between 14 patients) was 230.4 (30-1176) U/l. One patient died after the emergency bypass surgery. CONCLUSIONS: On the basis of initial results the authors emphasize the importance of working out the optimal revascularisation strategy for acute coronary syndrome patients with ST-segment elevation in every Hungarian catheter centre. The authors find this method--in their case the catheter laboratory is 60 kms away, time of transport is approximately 70-90 minutes--an effective and safe alternative therapy in patients under the age of 75 years with acute myocardial infarction.

Original languageHungarian
Pages (from-to)1583-1586
Number of pages4
JournalOrvosi Hetilap
Volume144
Issue number32
Publication statusPublished - Aug 10 2003

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Catheters
Acute Coronary Syndrome
Emergencies
Hematemesis
Bundle-Branch Block
Proxy
Tissue Plasminogen Activator
Complementary Therapies
ST Elevation Myocardial Infarction
Hematoma
Infarction
Glycoproteins
Myocardial Infarction
Therapeutics
eptifibatide

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Józan-Jilling, M., Horváth, I., Kis, E., Bodnár, I., Baross, M., Zsigmond, A., ... Papp, L. (2003). Facilitált revascularisatiós stratégia ST-elevációs myocardiuminfarctusban. Orvosi Hetilap, 144(32), 1583-1586.

Facilitált revascularisatiós stratégia ST-elevációs myocardiuminfarctusban. / Józan-Jilling, Mihály; Horváth, I.; Kis, Ernó; Bodnár, Imre; Baross, Magdolna; Zsigmond, Arpád; Kovács, Eva; Papp, L.

In: Orvosi Hetilap, Vol. 144, No. 32, 10.08.2003, p. 1583-1586.

Research output: Contribution to journalArticle

Józan-Jilling, M, Horváth, I, Kis, E, Bodnár, I, Baross, M, Zsigmond, A, Kovács, E & Papp, L 2003, 'Facilitált revascularisatiós stratégia ST-elevációs myocardiuminfarctusban.', Orvosi Hetilap, vol. 144, no. 32, pp. 1583-1586.
Józan-Jilling M, Horváth I, Kis E, Bodnár I, Baross M, Zsigmond A et al. Facilitált revascularisatiós stratégia ST-elevációs myocardiuminfarctusban. Orvosi Hetilap. 2003 Aug 10;144(32):1583-1586.
Józan-Jilling, Mihály ; Horváth, I. ; Kis, Ernó ; Bodnár, Imre ; Baross, Magdolna ; Zsigmond, Arpád ; Kovács, Eva ; Papp, L. / Facilitált revascularisatiós stratégia ST-elevációs myocardiuminfarctusban. In: Orvosi Hetilap. 2003 ; Vol. 144, No. 32. pp. 1583-1586.
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AU - Józan-Jilling, Mihály

AU - Horváth, I.

AU - Kis, Ernó

AU - Bodnár, Imre

AU - Baross, Magdolna

AU - Zsigmond, Arpád

AU - Kovács, Eva

AU - Papp, L.

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N2 - AIMS: The authors performed urgent coronarography and revascularisation after administering a combined half dose of alteplase (tissue plazminogen activator) and eptifibatide (glycoprotein II/bIIIa receptor blocking agent) to patients suffering from acute coronary syndromes with persistent ST-segment elevation. METHODS: During the period between 01 April to 15 December, 2001. 20 patients (16 men and 4 women, mean age: 55.6 years) were treated. The localization of infarction on the basis of ST-segment elevation was: 9 cases inferior, 10 cases anterior and patient with left bundle branch block in 1 cases. The mean time between the infarct related angina and hospital admission was 158 (30-600) minutes. The combined medical therapy was initiated after 34 (15-150) minutes on the average admission, and 123 (71-210) minutes later the patients were in the catheter laboratory. RESULTS: Coronarography showed TIMI-0 flow in 4 cases, TIMI-2 flow in 3 cases and TIMI-3 flow in 13 cases. Acute percutan coronary intervention was done in 14 cases, aorto-coronary bypass surgery was performed in 4 cases (2 of them were emergency operations, the other 2 were done electively). Besides postpunctional haematomas, hemorrhagic complications in the form of haematemesis were observed in 2 cases, but there was no need for transfusion. The mean CK-MB release (between 14 patients) was 230.4 (30-1176) U/l. One patient died after the emergency bypass surgery. CONCLUSIONS: On the basis of initial results the authors emphasize the importance of working out the optimal revascularisation strategy for acute coronary syndrome patients with ST-segment elevation in every Hungarian catheter centre. The authors find this method--in their case the catheter laboratory is 60 kms away, time of transport is approximately 70-90 minutes--an effective and safe alternative therapy in patients under the age of 75 years with acute myocardial infarction.

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