Facile synthesis of steroidal phenyl ketones via homogeneous catalytic carbonylation

R. Skoda-Földes, Zoltán Székvölgyi, L. Kollár, Z. Berente, Judit Horváth, Zoltán Tuba

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Steroidal phenyl ketones were synthesised in high yields by palladium- catalysed carbonylation reactions of 17-iodo-androst-16-ene derivatives in the presence of NaBPh4 under mild reaction conditions. Alkenyl bromides or enol triflates gave lower yields in the same reaction. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)3415-3418
Number of pages4
JournalTetrahedron
Volume56
Issue number21
Publication statusPublished - May 19 2000

Fingerprint

Carbonylation
Palladium
Ketones
Bromides
Derivatives
16-androstene

Keywords

  • Carbonylation
  • Pd-catalysis
  • Phenyl ketones
  • Steroids

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Facile synthesis of steroidal phenyl ketones via homogeneous catalytic carbonylation. / Skoda-Földes, R.; Székvölgyi, Zoltán; Kollár, L.; Berente, Z.; Horváth, Judit; Tuba, Zoltán.

In: Tetrahedron, Vol. 56, No. 21, 19.05.2000, p. 3415-3418.

Research output: Contribution to journalArticle

Skoda-Földes, R. ; Székvölgyi, Zoltán ; Kollár, L. ; Berente, Z. ; Horváth, Judit ; Tuba, Zoltán. / Facile synthesis of steroidal phenyl ketones via homogeneous catalytic carbonylation. In: Tetrahedron. 2000 ; Vol. 56, No. 21. pp. 3415-3418.
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