Expression of inositol 1,4,5-trisphosphate receptors in rat adrenocortical zones

G. Szabadkai, A. Horváth, T. Rohács, L. Vimláti, A. Spät, P. Enyedi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Previously we demonstrated the presence of InsP3R-I, -II and -III subtypes in the zona glomerulosa. Now we have examined the expression of different subtypes of inositol 1,4,5-trisphosphate receptor (InsP3R) in the inner zones of rat adrenal cortex. RNA extracted from decapsulated adrenal tissue (zonae fasciculata-reticularis and the medulla) or from fasciculata-reticularis cells was reverse transcribed. Subsequent polymerase chain reaction revealed the presence of InsP3R-I, -II and -III subtypes in decapsulated tissue but failed to demonstrate the expression of any known subtypes of InsP3R in fasciculata-reticularis cells. Accordingly, InsP3 receptors expressed in the decapsulated tissue are of medullary origin.

Original languageEnglish
Pages (from-to)13-17
Number of pages5
JournalJournal of Steroid Biochemistry and Molecular Biology
Volume57
Issue number1-2
DOIs
Publication statusPublished - Jan 1996

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Inositol 1,4,5-Trisphosphate Receptors
Rats
Tissue
Zona Reticularis
Zona Fasciculata
Zona Glomerulosa
Adrenal Cortex
Polymerase chain reaction
RNA
Polymerase Chain Reaction

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

Cite this

Expression of inositol 1,4,5-trisphosphate receptors in rat adrenocortical zones. / Szabadkai, G.; Horváth, A.; Rohács, T.; Vimláti, L.; Spät, A.; Enyedi, P.

In: Journal of Steroid Biochemistry and Molecular Biology, Vol. 57, No. 1-2, 01.1996, p. 13-17.

Research output: Contribution to journalArticle

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