Exposure to solvents in female patients with scleroderma

L. Czirják, G. Kumánovics

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The role of exposure to solvents was investigated in female patients with connective tissue disease and Raynaud's phenomenon using a questionnaire. Sixteen out of the 63 patients with systemic sclerosis had been exposed to solvents. A borderline significance was demonstrated compared to matched female controls (P <0.05). Fourteen out of the 66 patients with undifferentiated connective tissue disease, 18/86 of patients with Raynaud's phenomenon, 6/45 with systemic lupus erythematosus, 1/16 with dermato-polymyositis, 1/15 with rheumatoid arthritis and 0/13 with primary Sjögren's syndrome had been exposed to solvents. None of these groups of patients showed a statistical significance compared to matched controls. Our present findings indicate that, at least in certain areas of the world, exposure to solvents may be a provoking factor in female scleroderma, but it must be emphasised that only a borderline significance was found between the scleroderma patients and controls. A large multi-center study seems to be required to clarify the importance of solvents as provoking factors of scleroderma. Furthermore, exposure to solvents does not seem to be a provoking factor among females for the other connective tissue diseases.

Original languageEnglish
Pages (from-to)114-118
Number of pages5
JournalClinical Rheumatology
Volume21
Issue number2
Publication statusPublished - 2002

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Connective Tissue Diseases
Raynaud Disease
Polymyositis
Systemic Scleroderma
Systemic Lupus Erythematosus
Rheumatoid Arthritis

Keywords

  • Connective tissue disease
  • Lupus
  • Raynaud's phenomenon
  • Scleroderma
  • Solvents

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

Cite this

Exposure to solvents in female patients with scleroderma. / Czirják, L.; Kumánovics, G.

In: Clinical Rheumatology, Vol. 21, No. 2, 2002, p. 114-118.

Research output: Contribution to journalArticle

Czirják, L. ; Kumánovics, G. / Exposure to solvents in female patients with scleroderma. In: Clinical Rheumatology. 2002 ; Vol. 21, No. 2. pp. 114-118.
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