Exposure of consumers to deoxynivalenol from consumption of white bread in Hungary

A. Ámbrus, M. Szeitzne-Szabó, A. Zentai, J. Sali, I. J. Szabó

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

In view of the frequent occurrence of mycotoxins in cereals, a study was initiated to assess the exposure of the Hungarian adult population. Consumption data for 1360 individuals, based on a 3-day questionnaire, indicated that white bread accounted for the major intake of cereal-based products. Various cereal products were analysed for 16 mycotoxins by a LC/MS/MS multi-toxin method with LOD of 16 μgkg-1 and LOQ of 50 μgkg-1. Deoxynivalenol (DON) was most frequently detected, but no acetyl-deoxynivalenol was present in detectable concentrations. Consumer exposure was calculated with standard Monte Carlo probabilistic modelling and point estimates, taking into account bread consumption and DON contamination in independently taken wheat flour and wheat grain samples. Over 55% of cases the DON intake were below 15% of the provisional maximum tolerable daily intake (PMTDI) of 1 μg/(kg bw)/day. However, in 5-15% of cases, the intake from bread consumption alone exceeded the PMTDI. Wheat grain data led to the higher percentage. Intakes estimated from both data sets were at or below the acute reference dose (ARfD) of 8 μg/(kg bw)/day in 99.94-99.97% of cases.

Original languageEnglish
Pages (from-to)209-217
Number of pages9
JournalFood Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment
Volume28
Issue number2
DOIs
Publication statusPublished - Feb 2011

Fingerprint

white bread
Hungary
Bread
deoxynivalenol
Triticum
No-Observed-Adverse-Effect Level
acceptable daily intake
Mycotoxins
mycotoxins
breads
Cereal products
wheat
grain products
Flour
wheat flour
Contamination
toxins
questionnaires
dosage
Population

Keywords

  • Cereals
  • Exposure
  • Exposure assessment
  • Mycotoxins
  • Probabilistic modelling
  • Trichothecenes

ASJC Scopus subject areas

  • Food Science
  • Health, Toxicology and Mutagenesis
  • Public Health, Environmental and Occupational Health
  • Toxicology
  • Chemistry(all)

Cite this

Exposure of consumers to deoxynivalenol from consumption of white bread in Hungary. / Ámbrus, A.; Szeitzne-Szabó, M.; Zentai, A.; Sali, J.; Szabó, I. J.

In: Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment, Vol. 28, No. 2, 02.2011, p. 209-217.

Research output: Contribution to journalArticle

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