Experimental model for liver metastasis formation using lewis lung tumor

L. Kopper, T. Van Hanh, K. Lapis

Research output: Contribution to journalArticle

77 Citations (Scopus)


A new experimental model is introduced for liver metastases using intrasplenically injected Lewis lung tumor cells. The appearance of liver metastases was studied in the presence and after the removal of primary tumor. The tumorous foci in the liver proved to be natural metastases and increased in number blocking the activity of the Kupffer cells by carragheenan. This model provides a useful tool to study different aspects of liver metastases.

Original languageEnglish
Pages (from-to)31-38
Number of pages8
JournalJournal of cancer research and clinical oncology
Issue number1
Publication statusPublished - Mar 1 1982


  • Carragheenan
  • Kupffer cells
  • Lewis lung tumor
  • Liver metastasis

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Experimental model for liver metastasis formation using lewis lung tumor'. Together they form a unique fingerprint.

  • Cite this