Experimental infection of lambs with reovirus type I isolated from sheep

S. Belak, V. Pálfi

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

Lambs were infected experimentally with reovirus strain type 1 (H/11) isolated from sheep during a field epidemic. After an incubation period of 4 to 6 days a rise in temperature by 0.6 to 0.9°C, ocular and nasal discharge, sneezing, dyspnea and diarrhea could be observed in 2 to 4 wk old lambs infected intratracheally and intranasally. Enteritis, catarrh of the upper airways and diffuse interstitial pneumonia were found in a lamb killed 8 days post infection (p.i.). The symptoms worsened in a lamb of lowered vitality and this animal died on day 11 p.i. Necropsy revealed enteritis, catarrh of the upper respiratory tract and multifocal catarrhal pneumonia. Clinical signs ceased in the survivors at the end of the 3rd wk, and specific neutralizing antibodies against the H/11 strain at titers between 1:64 and 1:128 appeared in the convalescent sera. Virus could be reisolated from the nasal and rectal swabs between 4 and 9 days p.i. On the basis of the experimental infection and field cases it is concluded that reoviruses play an active role in the etiology of respiratory and intestinal diseases of young lambs.

Original languageEnglish
Title of host publicationACTA VET.ACAD.SCI.HUNG.
Pages241-247
Number of pages7
Volume24
Edition3
Publication statusPublished - 1974

Fingerprint

Sheep
Common Cold
Enteritis
Infection
Nose
Mammalian Orthoreovirus
Sneezing
Bronchopneumonia
Intestinal Diseases
Interstitial Lung Diseases
Neutralizing Antibodies
Respiratory System
Dyspnea
Diarrhea
Viruses
Temperature
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Belak, S., & Pálfi, V. (1974). Experimental infection of lambs with reovirus type I isolated from sheep. In ACTA VET.ACAD.SCI.HUNG. (3 ed., Vol. 24, pp. 241-247)

Experimental infection of lambs with reovirus type I isolated from sheep. / Belak, S.; Pálfi, V.

ACTA VET.ACAD.SCI.HUNG.. Vol. 24 3. ed. 1974. p. 241-247.

Research output: Chapter in Book/Report/Conference proceedingChapter

Belak, S & Pálfi, V 1974, Experimental infection of lambs with reovirus type I isolated from sheep. in ACTA VET.ACAD.SCI.HUNG.. 3 edn, vol. 24, pp. 241-247.
Belak S, Pálfi V. Experimental infection of lambs with reovirus type I isolated from sheep. In ACTA VET.ACAD.SCI.HUNG.. 3 ed. Vol. 24. 1974. p. 241-247
Belak, S. ; Pálfi, V. / Experimental infection of lambs with reovirus type I isolated from sheep. ACTA VET.ACAD.SCI.HUNG.. Vol. 24 3. ed. 1974. pp. 241-247
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