Experience with endeavor stent implantations

Géza Lupkovics, András Kenéz, Zoltán Németh, Ákos Motyovszki, István Takács, E. Papp

Research output: Contribution to journalArticle

Abstract

Restenosis is the most common disadvantage of percutaneous coronary interventions. The incidence of restenosis can be lowered with the use of stents. After the use of stents, 'in-stent' restenosis can occur. To avoid it drug-eluting stents were developed, but the occurrence of stent thrombosis is higher than observed in case of bare-metal stents. Endeavor is a new zotarolimus-eluting stent developed to reduce the stent thrombosis. Aims In a prospective study we aimed to follow-up our patients regarding the incidence of in-stent restenosis, stent thrombosis, and clinical end points after Endeavor stent implantation. Patients and methods Endeavor stents have been implanted in patients undergoing coronary angiography with the following indications: complex lesions susceptible to restenosis and after recanalization of chronic total occlusions. Results Endeavor stent implantations were successfully performed in 99 patients and has been successful in 98% of cases, two stents could not be implanted because of technical difficulties. Significant restenosis was observed in eight patients (8.1%). Subacute stent thrombosis (within 10 days) occurred in two patients (2.0%). Any late stent thrombosis was not observed. Conclusion Our registry affirmed the results of the Endeavor I trial in a population with more severe and longer coronary stenosis. We can conclude that the Endeavor stent is suitable for implantation in complex, longer coronary lesions. Our long-term follow-up data do not prove those opinions which prefer bare-metal stent implantation in all patients because of the late adverse events of the drug-eluting stents.

Original languageEnglish
Pages (from-to)421-423
Number of pages3
JournalCoronary Artery Disease
Volume19
Issue number6
DOIs
Publication statusPublished - Sep 2008

Fingerprint

Stents
Thrombosis
Drug-Eluting Stents
Metals
Coronary Stenosis
Incidence
Percutaneous Coronary Intervention
Coronary Angiography
Registries

Keywords

  • Endeavor stent
  • In-stent restenosis
  • Stent thrombosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Lupkovics, G., Kenéz, A., Németh, Z., Motyovszki, Á., Takács, I., & Papp, E. (2008). Experience with endeavor stent implantations. Coronary Artery Disease, 19(6), 421-423. https://doi.org/10.1097/MCA.0b013e328304a243

Experience with endeavor stent implantations. / Lupkovics, Géza; Kenéz, András; Németh, Zoltán; Motyovszki, Ákos; Takács, István; Papp, E.

In: Coronary Artery Disease, Vol. 19, No. 6, 09.2008, p. 421-423.

Research output: Contribution to journalArticle

Lupkovics, G, Kenéz, A, Németh, Z, Motyovszki, Á, Takács, I & Papp, E 2008, 'Experience with endeavor stent implantations', Coronary Artery Disease, vol. 19, no. 6, pp. 421-423. https://doi.org/10.1097/MCA.0b013e328304a243
Lupkovics G, Kenéz A, Németh Z, Motyovszki Á, Takács I, Papp E. Experience with endeavor stent implantations. Coronary Artery Disease. 2008 Sep;19(6):421-423. https://doi.org/10.1097/MCA.0b013e328304a243
Lupkovics, Géza ; Kenéz, András ; Németh, Zoltán ; Motyovszki, Ákos ; Takács, István ; Papp, E. / Experience with endeavor stent implantations. In: Coronary Artery Disease. 2008 ; Vol. 19, No. 6. pp. 421-423.
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