Exophiala dermatitidis Endophthalmitis: Case Report and Literature Review

Mónika Homa, Palanisamy Manikandan, Veerappan Saravanan, Rajaraman Revathi, Raghavan Anita, Venkatapathy Narendran, Kanesan Panneerselvam, Coimbatore Subramanian Shobana, Mohammed Al Aidarous, László Galgóczy, Csaba Vágvölgyi, Tamás Papp, László Kredics

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3 Citations (Scopus)

Abstract

We report a case of a 59-year-old male patient with a postoperative fungal infection of the left eye. A dark-pigmented yeast, Exophiala dermatitidis (previously known as Wangiella dermatitidis), was identified from the culture of the biopsy taken from the posterior capsule. The infection was successfully eradicated by a combination of surgical and medical (i.e., voriconazole and fluconazole) treatment. This is the first report of successfully treated E. dermatitidis endophthalmitis, which demonstrates that a prompt and aggressive antifungal therapy combined with surgical intervention is necessary to prevent vision loss in cases of endophthalmitis due to Exophiala species. Beside the case description, we also aim to provide a literature review of previously reported eye infections caused by Exophiala species in order to help the future diagnosis and management of the disease.

Original languageEnglish
Pages (from-to)603-609
Number of pages7
JournalMycopathologia
Volume183
Issue number3
DOIs
Publication statusPublished - Jun 1 2018

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Keywords

  • Antifungal susceptibility
  • Dematiaceous fungi
  • Endophthalmitis
  • Exophiala
  • Keratitis

ASJC Scopus subject areas

  • Microbiology
  • Applied Microbiology and Biotechnology
  • Agronomy and Crop Science
  • veterinary (miscalleneous)

Cite this

Homa, M., Manikandan, P., Saravanan, V., Revathi, R., Anita, R., Narendran, V., Panneerselvam, K., Shobana, C. S., Aidarous, M. A., Galgóczy, L., Vágvölgyi, C., Papp, T., & Kredics, L. (2018). Exophiala dermatitidis Endophthalmitis: Case Report and Literature Review. Mycopathologia, 183(3), 603-609. https://doi.org/10.1007/s11046-017-0235-4