Exhaled methane concentration profiles during exercise on an ergometer

A. Szabó, V. Ruzsanyi, K. Unterkofler, A. Mohácsi, E. Tuboly, M. Borós, G. Szabó, H. Hinterhuber, A. Amann

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Exhaled methane concentration measurements are extensively used in medical investigation of certain gastrointestinal conditions. However, the dynamics of endogenous methane release is largely unknown. Breath methane profiles during ergometer tests were measured by means of a photoacoustic spectroscopy based sensor. Five methane-producing volunteers (with exhaled methane level being at least 1 ppm higher than room air) were measured. The experimental protocol consisted of 5 min rest - 15 min pedalling (at a workload of 75 W) - 5 min rest. In addition, hemodynamic and respiratory parameters were determined and compared to the estimated alveolar methane concentration. The alveolar breath methane level decreased considerably, by a factor of 3-4 within 1.5 min, while the estimated ventilation-perfusion ratio increased by a factor of 2-3. Mean pre-exercise and exercise methane concentrations were 11.4 ppm (SD:7.3) and 2.8 ppm (SD:1.9), respectively. The changes can be described by the high sensitivity of exhaled methane to ventilation-perfusion ratio and are in line with the Farhi equation.

Original languageEnglish
Article number016009
JournalJournal of Breath Research
Volume9
Issue number1
DOIs
Publication statusPublished - Mar 1 2015

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Methane
Exercise
Ventilation-Perfusion Ratio
Workload
Foot
Volunteers
Spectrum Analysis
Hemodynamics
Air

Keywords

  • Farhi equation
  • methane breath test
  • photoacoustic spectroscopy
  • spirometer

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Medicine(all)

Cite this

Exhaled methane concentration profiles during exercise on an ergometer. / Szabó, A.; Ruzsanyi, V.; Unterkofler, K.; Mohácsi, A.; Tuboly, E.; Borós, M.; Szabó, G.; Hinterhuber, H.; Amann, A.

In: Journal of Breath Research, Vol. 9, No. 1, 016009, 01.03.2015.

Research output: Contribution to journalArticle

Szabó, A, Ruzsanyi, V, Unterkofler, K, Mohácsi, A, Tuboly, E, Borós, M, Szabó, G, Hinterhuber, H & Amann, A 2015, 'Exhaled methane concentration profiles during exercise on an ergometer', Journal of Breath Research, vol. 9, no. 1, 016009. https://doi.org/10.1088/1752-7155/9/1/016009
Szabó, A. ; Ruzsanyi, V. ; Unterkofler, K. ; Mohácsi, A. ; Tuboly, E. ; Borós, M. ; Szabó, G. ; Hinterhuber, H. ; Amann, A. / Exhaled methane concentration profiles during exercise on an ergometer. In: Journal of Breath Research. 2015 ; Vol. 9, No. 1.
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