Exhaled breath volatile alterations in pregnancy assessed with electronic nose

Andras Bikov, Judit Pako, Dorottya Kovacs, Lilla Tamasi, Zsofia Lazar, Janos Rigo, Gyorgy Losonczy, Ildiko Horvath

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Context: Pregnancy-linked accelerated metabolism and oxidative stress may alter the exhaled volatile compound pattern ("breathprint"). Electronic noses can distinguish "breathprints" associated with different disorders. Objective: This is the first study assessing alterations in "breathprint" during gestation. Material and methods: 130 women participated in our study (78 pregnant vs. 52 non-pregnant). Breath samples were processed by an electronic nose and analyzed using principal component analysis. Results: Significant differences were found in exhaled breath pattern between pregnant and non-pregnant women (p=0.001). Conclusion: Pregnancy-induced changes in exhaled gases need to be considered when pregnant women with respiratory disorders carry out breath tests.

Original languageEnglish
Pages (from-to)476-484
Number of pages9
JournalBiomarkers
Volume16
Issue number6
DOIs
Publication statusPublished - Sep 1 2011

Keywords

  • Pregnancy
  • breath test
  • electronic nose

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Health, Toxicology and Mutagenesis

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