Végrehajtó funkciók zavara frontális károsodásokban es frontális epilepsziában.

Translated title of the contribution: Executive dysfunction in frontal lesions and frontal epilepsy

Zsanett Tárnok, P. Barsi, J. Gádoros, P. Halász

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

BACKGROUND: To explore the functions of the frontal lobe that are associated with high order cognitive and behavioral aspects such as the organization and execution of thoughts and behavior by neuropsychological methods is difficult. These so called executive functions are in close connection with the prefrontal thalamocortical circuits, damage of which can cause deficits in cognitive functions and even changes in personality. METHODS: The aim of this study is to present a neuropsychological battery for testing frontal lobe functions. 31 patients (with frontal epilepsy and/or frontal lesion) and 38 healthy control subjects participated in the study. The control subjects were matched to the patient group in age, gender and education. RESULTS: Comparing to the controls the patient group showed significant deficits in most of the measured executive functions, except two tests which show that the short time selective attention is preserved. We divided the patient group into three subgroups (frontal epilepsy only FLE, frontal lesion only FL, frontal lesion and epilepsy FLE+FL) and we found that except working memory deficits and problems in inhibition, there were no difference between the FLE patients and the control group. We found most frequently perseveration and errors in a strategy making task among the FL (mainly medial) patients. We didn't find any difference in these tests according to the lateralization of the lesion. CONCLUSION: In conclusion we found that working memory deficits and problems in inhibition differentiated the frontal patient group from the controls in all cases. We emphasize that in frontal epilepsy (with no reported MR lesion) there are the same type, however more limited neuropsychological alterations as in lesional frontal dysfunction.

Original languageHungarian
Pages (from-to)269-280
Number of pages12
JournalIdeggyógyászati szemle
Volume59
Issue number7-8
Publication statusPublished - Jul 20 2006

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Epilepsy
Executive Function
Memory Disorders
Frontal Lobe
Short-Term Memory
Control Groups
Cognition
Personality
Healthy Volunteers
Age Groups
Education

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Végrehajtó funkciók zavara frontális károsodásokban es frontális epilepsziában. / Tárnok, Zsanett; Barsi, P.; Gádoros, J.; Halász, P.

In: Ideggyógyászati szemle, Vol. 59, No. 7-8, 20.07.2006, p. 269-280.

Research output: Contribution to journalArticle

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