Exchangeable body sodium in normal man: analysis of various frames of reference.

R. de Châtel, A. Tislér, M. Herendi, I. Barna, M. Tóth, I. Krasznai

Research output: Contribution to journalArticle


Exchangeable sodium is a reliable measure of body sodium contents. Since fat tissue contains significantly less sodium per unit of weight than other tissues, leanness of an individual may considerably affect exchangeable body sodium. Thus, subjects of different body size can be compared only when body build is considered. To evaluate various frames of reference, we analysed the relationship between exchangeable sodium as determined by isotope dilution and various parameters of body size. Body weight, body height, body surface area, and leanness index correlated significantly with exchangeable sodium, the closest relationship having been obtained with body surface area (r = 0.790; p less than 0.001). When analysing males and females separately (n = 18 and 36, resp.), best parallelism of regression lines was also obtained with body surface area. It is concluded that exchangeable sodium should be referred to unit of body surface area, expressing each individual's value as percent of the normal predicted value calculated from the regression equations y = 1388x + 370 and y = 1554x - 196 for males and females, respectively.

Original languageEnglish
Pages (from-to)359-366
Number of pages8
JournalActa physiologica Hungarica
Issue number3-4
Publication statusPublished - 1988


ASJC Scopus subject areas

  • Physiology (medical)

Cite this

de Châtel, R., Tislér, A., Herendi, M., Barna, I., Tóth, M., & Krasznai, I. (1988). Exchangeable body sodium in normal man: analysis of various frames of reference. Acta physiologica Hungarica, 72(3-4), 359-366.