Examining the Vitamin D Status of Children With Solid Tumors

Orsolya Juhász, Zsuzsanna Jakab, András Szabó, Miklós Garami

Research output: Contribution to journalArticle

Abstract

Objective: Our aims were to compare the vitamin D status of children with and without cancer and to examine the possible correlation between vitamin D levels in children with cancer before initiating treatment and prognosis. Method: We compared the data of 173 children with cancer with those of 569 children without cancer. Results: We measured a significant difference (p = 1.34E–08) between the vitamin D levels of children with cancer before treatment and children without cancer. There was a significant correlation between the initial vitamin D levels of children with cancer and the prognosis (p = 0.016, odds ratio = 51.33) at 5% significance. Conclusions: The average vitamin D level was 19.76% lower in the population with cancer compared with the average of the control group, and we found a correlation between the lower vitamin D levels in children with cancer and the adverse prognosis. We suggest that supplying vitamin D is reasonable and a prospective study of vitamin D in pediatric patients with cancer is recommended.

Original languageEnglish
Pages (from-to)128-134
Number of pages7
JournalJournal of the American College of Nutrition
Volume39
Issue number2
DOIs
Publication statusPublished - Feb 17 2020

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Keywords

  • Vitamin D
  • oncology prognosis
  • pediatric oncology
  • supplementation

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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