Examination of the role of oxygen free radicals in bronchial asthma in childhood

Z. Novák, I. Németh, K. Gyurkovits, Sz I. Varga, B. Matkovics

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The antioxidant enzyme activities, the lipid peroxidation level, the parameters of glutathione metabolism, and the proportion of haemoglobin oxidation products were determined during the symptom-free period of childhood bronchial asthma. A decreased catalase activity and a significantly reduced glutathione instability were demonstrated as compared to the controls. The results indicate that antioxidant protection of the haemoglobin molecule in asthmatic children is considerably decreased.

Original languageEnglish
Pages (from-to)247-251
Number of pages5
JournalClinica Chimica Acta
Volume201
Issue number3
DOIs
Publication statusPublished - Sep 30 1991

Keywords

  • Antioxidant enzymes
  • Asthma bronchiale
  • Lipid peroxidation
  • Oxidative sensitivity
  • Red blood cells

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Biochemistry, medical

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