Examination of the aromatic amination catalyzed by palladium on charcoal

Anna Komáromi, Z. Novák

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The Buchwald-Hartwig amination of aryl halides with secondary amines and functionalized aromatic amines catalyzed by solid-supported palladium is reported. The choices of ligand, base and solvent are crucial for the successful coupling. The ami-nation of aromatic iodides, bromides and chlorides can be easily achieved with palladium on charcoal in the presence of a biphenylphosphane-type ligand at 80-110 °C. In addition, the palladium on charcoal catalyst is easily separable after the reaction, and reusable several times with only small activity loss.

Original languageEnglish
Pages (from-to)1523-1532
Number of pages10
JournalAdvanced Synthesis and Catalysis
Volume352
Issue number9
DOIs
Publication statusPublished - Jun 1 2010

Fingerprint

Amination
Charcoal
Palladium
Amines
Ligands
Iodides
Bromides
Chlorides
Catalysts

Keywords

  • Amination
  • Arylation
  • Catalyst recycling
  • Cross-coupling
  • Palladium on carbon

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

Cite this

Examination of the aromatic amination catalyzed by palladium on charcoal. / Komáromi, Anna; Novák, Z.

In: Advanced Synthesis and Catalysis, Vol. 352, No. 9, 01.06.2010, p. 1523-1532.

Research output: Contribution to journalArticle

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