Examination of subepithelial scarring with ultrasound biomicroscopy following photorefractive keratectomy

Z. Z. Nagy, J. Németh, B. Csákány, I. Süveges

Research output: Contribution to journalArticle

Abstract

Subepithelial haze and concomittant refractive regression are the most important complications of photorefractive keratectomies (PRK) in the higher diopter range. Twenty previously photokeratectomized myopic eyes, which showed a certain level of subepithelial scarring, were examined in the present study. The range of PRK treatment varied between -4.0 and -12.0 D (on average -7.4 ± 3.88 D). Subsequent subepithelial haze was graded between 0.5 and 4.0, according to Hanna et al. The first ultrasound biomicroscopy (UBM) was performed between 1 and 3 months following PRK with the 50-80 MHz transducer of a Zeiss-Humphrey Model 840 ultrasound biomicroscope. A control UBM examination was carried out in each patient 3 months after the initial assessment. The severity of subepithelial haze correlated with the previous photo-ablation depth. Below and including Haze Grade 2.0, UBM showed loss of the Bowman's membrane and a slight thinning of the central 5.5 mm diameter cornea. Above Grade 2.0, the reflectivity of the anterior stromal parts began to increase. Between Grades 3.0 and 4.0, a hyper-reflective one-third of the anterior stroma with irregular borders was observed. In conclusion, haze graded below 2.0 was not observable with UBM. Haze graded more than 2.0 caused increased anterior stromal reflectivity in the central cornea. Ultrasound biomicroscopy was found to be a suitable method for presenting and following data over time for each patient with serious haze phenomena after excimer laser photo-ablation.

Original languageEnglish
Pages (from-to)113-116
Number of pages4
JournalLasers in Medical Science
Volume12
Issue number2
Publication statusPublished - Jun 1997

Fingerprint

Acoustic Microscopy
Photorefractive Keratectomy
Cicatrix
Cornea
Bowman Membrane
Excimer Lasers
Laser Therapy
Transducers

Keywords

  • Hyper-reflectivity
  • Photorefractive keratectomy
  • Subepithelial haze
  • Ultrasound biomicroscopy

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Surgery

Cite this

Examination of subepithelial scarring with ultrasound biomicroscopy following photorefractive keratectomy. / Nagy, Z. Z.; Németh, J.; Csákány, B.; Süveges, I.

In: Lasers in Medical Science, Vol. 12, No. 2, 06.1997, p. 113-116.

Research output: Contribution to journalArticle

@article{bcdd1c9d7a4c42a2998c5033c327ed8e,
title = "Examination of subepithelial scarring with ultrasound biomicroscopy following photorefractive keratectomy",
abstract = "Subepithelial haze and concomittant refractive regression are the most important complications of photorefractive keratectomies (PRK) in the higher diopter range. Twenty previously photokeratectomized myopic eyes, which showed a certain level of subepithelial scarring, were examined in the present study. The range of PRK treatment varied between -4.0 and -12.0 D (on average -7.4 ± 3.88 D). Subsequent subepithelial haze was graded between 0.5 and 4.0, according to Hanna et al. The first ultrasound biomicroscopy (UBM) was performed between 1 and 3 months following PRK with the 50-80 MHz transducer of a Zeiss-Humphrey Model 840 ultrasound biomicroscope. A control UBM examination was carried out in each patient 3 months after the initial assessment. The severity of subepithelial haze correlated with the previous photo-ablation depth. Below and including Haze Grade 2.0, UBM showed loss of the Bowman's membrane and a slight thinning of the central 5.5 mm diameter cornea. Above Grade 2.0, the reflectivity of the anterior stromal parts began to increase. Between Grades 3.0 and 4.0, a hyper-reflective one-third of the anterior stroma with irregular borders was observed. In conclusion, haze graded below 2.0 was not observable with UBM. Haze graded more than 2.0 caused increased anterior stromal reflectivity in the central cornea. Ultrasound biomicroscopy was found to be a suitable method for presenting and following data over time for each patient with serious haze phenomena after excimer laser photo-ablation.",
keywords = "Hyper-reflectivity, Photorefractive keratectomy, Subepithelial haze, Ultrasound biomicroscopy",
author = "Nagy, {Z. Z.} and J. N{\'e}meth and B. Cs{\'a}k{\'a}ny and I. S{\"u}veges",
year = "1997",
month = "6",
language = "English",
volume = "12",
pages = "113--116",
journal = "Lasers in Medical Science",
issn = "0268-8921",
publisher = "Springer London",
number = "2",

}

TY - JOUR

T1 - Examination of subepithelial scarring with ultrasound biomicroscopy following photorefractive keratectomy

AU - Nagy, Z. Z.

AU - Németh, J.

AU - Csákány, B.

AU - Süveges, I.

PY - 1997/6

Y1 - 1997/6

N2 - Subepithelial haze and concomittant refractive regression are the most important complications of photorefractive keratectomies (PRK) in the higher diopter range. Twenty previously photokeratectomized myopic eyes, which showed a certain level of subepithelial scarring, were examined in the present study. The range of PRK treatment varied between -4.0 and -12.0 D (on average -7.4 ± 3.88 D). Subsequent subepithelial haze was graded between 0.5 and 4.0, according to Hanna et al. The first ultrasound biomicroscopy (UBM) was performed between 1 and 3 months following PRK with the 50-80 MHz transducer of a Zeiss-Humphrey Model 840 ultrasound biomicroscope. A control UBM examination was carried out in each patient 3 months after the initial assessment. The severity of subepithelial haze correlated with the previous photo-ablation depth. Below and including Haze Grade 2.0, UBM showed loss of the Bowman's membrane and a slight thinning of the central 5.5 mm diameter cornea. Above Grade 2.0, the reflectivity of the anterior stromal parts began to increase. Between Grades 3.0 and 4.0, a hyper-reflective one-third of the anterior stroma with irregular borders was observed. In conclusion, haze graded below 2.0 was not observable with UBM. Haze graded more than 2.0 caused increased anterior stromal reflectivity in the central cornea. Ultrasound biomicroscopy was found to be a suitable method for presenting and following data over time for each patient with serious haze phenomena after excimer laser photo-ablation.

AB - Subepithelial haze and concomittant refractive regression are the most important complications of photorefractive keratectomies (PRK) in the higher diopter range. Twenty previously photokeratectomized myopic eyes, which showed a certain level of subepithelial scarring, were examined in the present study. The range of PRK treatment varied between -4.0 and -12.0 D (on average -7.4 ± 3.88 D). Subsequent subepithelial haze was graded between 0.5 and 4.0, according to Hanna et al. The first ultrasound biomicroscopy (UBM) was performed between 1 and 3 months following PRK with the 50-80 MHz transducer of a Zeiss-Humphrey Model 840 ultrasound biomicroscope. A control UBM examination was carried out in each patient 3 months after the initial assessment. The severity of subepithelial haze correlated with the previous photo-ablation depth. Below and including Haze Grade 2.0, UBM showed loss of the Bowman's membrane and a slight thinning of the central 5.5 mm diameter cornea. Above Grade 2.0, the reflectivity of the anterior stromal parts began to increase. Between Grades 3.0 and 4.0, a hyper-reflective one-third of the anterior stroma with irregular borders was observed. In conclusion, haze graded below 2.0 was not observable with UBM. Haze graded more than 2.0 caused increased anterior stromal reflectivity in the central cornea. Ultrasound biomicroscopy was found to be a suitable method for presenting and following data over time for each patient with serious haze phenomena after excimer laser photo-ablation.

KW - Hyper-reflectivity

KW - Photorefractive keratectomy

KW - Subepithelial haze

KW - Ultrasound biomicroscopy

UR - http://www.scopus.com/inward/record.url?scp=0030961247&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030961247&partnerID=8YFLogxK

M3 - Article

VL - 12

SP - 113

EP - 116

JO - Lasers in Medical Science

JF - Lasers in Medical Science

SN - 0268-8921

IS - 2

ER -