Examination of early cleavage and its importance in IVF treatment

Peter Fancsovits, F. Z. Takács, G. Z. Tóthné, Z. Papp, J. Urbancsek

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Since the introduction of assisted reproduction, the number of multiple pregnancies has increased due to the high number of transferred embryos. There is an urgent need for IVF specialists to reduce the number of embryos transferred without the risk of decreasing pregnancy rates. Embryos are selected for transfer on the basis of their developmental stage and morphology. The number of blastomeres of the embryo indicates the speed of early embryo development which correlates to the viability of the embryo. Examination of early embryo development, especially the timing of the first cleavage, can be recommended as a tool for predicting embryo viability. Observation of timing of the first cleavage and its different stages helps us to identify fast- and slow-developing embryos. Early pronuclear breakdown and early cleavage of the zygote are indicators of fast embryo development and good embryo viability. Thereby, they can lead to high implantation and pregnancy rates. The aim of this paper is to provide an overview of the timing of early embryo development and to show its significance in IVF treatment.

Original languageEnglish
Pages (from-to)367-372
Number of pages6
JournalJournal fur Reproduktionsmedizin und Endokrinologie
Volume3
Issue number6
Publication statusPublished - 2006

Fingerprint

Embryonic Structures
Embryonic Development
Pregnancy Rate
Therapeutics
Blastomeres
Multiple Pregnancy
Zygote
Embryo Transfer
Reproduction
Observation

Keywords

  • Cell cycle
  • Early cleavage
  • Embryo quality
  • In-vitro-fertilisation
  • Pronuclear breakdown

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Endocrinology

Cite this

Examination of early cleavage and its importance in IVF treatment. / Fancsovits, Peter; Takács, F. Z.; Tóthné, G. Z.; Papp, Z.; Urbancsek, J.

In: Journal fur Reproduktionsmedizin und Endokrinologie, Vol. 3, No. 6, 2006, p. 367-372.

Research output: Contribution to journalArticle

Fancsovits, Peter ; Takács, F. Z. ; Tóthné, G. Z. ; Papp, Z. ; Urbancsek, J. / Examination of early cleavage and its importance in IVF treatment. In: Journal fur Reproduktionsmedizin und Endokrinologie. 2006 ; Vol. 3, No. 6. pp. 367-372.
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