A case-control study was performed in two large-scale dairy herds on cows with at least two parturitions to evaluate the influence of certain risk factors on the development of puerperal metritis (PM), i. e. (1) manual intervention at calving; (2) retained foetal membranes (RFM) and (3) uncompensated negative energy balance characterized by (3/a) ketonuria or (3/b) hyperketonaemia. Cows suffering from PM were divided into two subgroups: those of showing only local symptoms of PM were considered as 'mild' (mPM) cases, the ones that developed systemic signs (fever, dullness), as well were characterized as "toxic" PM (tPM). Cows with normal involution were used as controls. Manual intervention (assistance) at calving as well as RFM had a significant effect (<0.001) on the frequency of PM [odds ratios (OR) 6.7 and 13.5 in univariable regression model], in case of RFM the more severe form of PM developed more frequently (OR: 3.9). Both hyperketonaemia and ketonuria, as signs of the negative energy balance of the cow, significantly increased the probability of PM and predisposed to the toxic form (ORs hyperketonaemia PM: 6.1, tPM: 6.3; ketonuria PM: 3.7, tPM: 14.0). A multivariable logistic regression model was built using the above variable and other influencing factors (proved to be significant), such as (i) >9400 I previous lactational milk yield (OR to tPM: 23.1); (ii) decreasing milk yield (OR to PM: 9.1, to tPM: 6.7) and (iii) increasing rectal temperature (OR to PM: 16.3, to tPM: 12.5) both between the 3rd and 5th days postpartum, were also included to improve the accuracy of the model. It was also demonstrated that increasing parity predispose to the more severe form of the disease (OR to tPM: 3.1).
|Number of pages||8|
|Journal||Magyar Allatorvosok Lapja|
|Publication status||Published - Jan 1 2012|
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