Evaluation of thyroid function and anti-thyroid autoantibodies in systemic sclerosis

I. Molnar, C. Balazs, E. Szabo, L. Czirjak

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9 Citations (Scopus)

Abstract

Parameters of thyroid metabolism, and the presence of anti-thyroid antibodies were investigated in 43 patients with systemic sclerosis. Anti-thyroid antibodies were detected in 14 cases. Elevated levels of anti-thyroglobulin antibodies were determined in 4 cases, anti-thyroid peroxidase (TPO) antibodies in 11, and anti-microsomal antibodies in 5. The detection of anti-TPO antibodies gave the most remarkable information about the presence of autoimmune thyroiditis. The patients with anti-TPO and/or reduced T3 concentration tended to have secondary Sjogren's syndrome. Our results provide further evidence that anti-thyroid antibodies might be responsible for the remarkable appearance of autoimmune thyroiditis in systemic sclerosis.

Original languageEnglish
Pages (from-to)112-114
Number of pages3
JournalActa Dermato-Venereologica
Volume72
Issue number2
Publication statusPublished - Jan 1 1992

Keywords

  • Anti-thyroid peroxidase antibody
  • Thyroid hormones

ASJC Scopus subject areas

  • Dermatology

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