Evaluation of the mechanical properties of the anterior lens capsule following femtosecond laser capsulotomy at different pulse energy settings

Gábor L. Sándor, Zoltán Kiss, Zoltán I. Bocskai, K. Kolev, A. Takács, Éva Juhász, Kinga Kránitz, Gábor Tóth, Andrea Gyenes, Imre Bojtár, Tibor Juhász, Zoltán Z. Nagy

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

PURPOSE: To evaluate and compare the mechanical properties of anterior capsule opening performed with femtosecond laser capsulotomy at different energy settings in ex vivo porcine anterior lens capsule specimens. METHODS: Twenty-five fresh porcine eyes per group were included in the study. Femtosecond laser capsulotomy was performed with three different pulse energy levels: 2 μJ (low energy group), 5 μJ (intermediate energy group), and 10 μJ (high energy group). The capsule openings were stretched with universal testing equipment until they ruptured. The morphologic profile of the cut capsule edges was evaluated using scanning electron microscopy. RESULTS: The high energy group had significantly lower rupture force (108 ± 14 mN) compared to the intermediate energy group (118 ± 10 mN) (P <.05) and low energy group (119 ± 11 mN) (P <.05), but the difference between the intermediate energy and low energy groups was not significant (P = .9479). The high energy group had significantly lower circumference stretching ratio (144% ± 3%) compared to the intermediate energy group (148%± 3%) (P <.05) and low energy group (148% ± 3%) (P <.05), but the difference between the intermediate energy group and low energy group was not significant (P = .9985). Scanning electron microscopy images showed that the edge was only serrated with low and intermediate energy, but additional signs of collagen melting and denaturation were observed at high energy. CONCLUSIONS: Anterior capsule openings created at a high energy level were slightly weaker and less extensible than those created at low or intermediate levels, possibly due to the increased thermal effect of photodisruption.

Original languageEnglish
Pages (from-to)153-157
Number of pages5
JournalJournal of Refractive Surgery
Volume31
Issue number3
DOIs
Publication statusPublished - Mar 1 2015

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Anterior Capsule of the Lens
Capsules
Lasers
Electron Scanning Microscopy
Swine
Freezing
Rupture
Collagen
Hot Temperature
Equipment and Supplies

ASJC Scopus subject areas

  • Ophthalmology
  • Surgery
  • Medicine(all)

Cite this

Evaluation of the mechanical properties of the anterior lens capsule following femtosecond laser capsulotomy at different pulse energy settings. / Sándor, Gábor L.; Kiss, Zoltán; Bocskai, Zoltán I.; Kolev, K.; Takács, A.; Juhász, Éva; Kránitz, Kinga; Tóth, Gábor; Gyenes, Andrea; Bojtár, Imre; Juhász, Tibor; Nagy, Zoltán Z.

In: Journal of Refractive Surgery, Vol. 31, No. 3, 01.03.2015, p. 153-157.

Research output: Contribution to journalArticle

Sándor, Gábor L. ; Kiss, Zoltán ; Bocskai, Zoltán I. ; Kolev, K. ; Takács, A. ; Juhász, Éva ; Kránitz, Kinga ; Tóth, Gábor ; Gyenes, Andrea ; Bojtár, Imre ; Juhász, Tibor ; Nagy, Zoltán Z. / Evaluation of the mechanical properties of the anterior lens capsule following femtosecond laser capsulotomy at different pulse energy settings. In: Journal of Refractive Surgery. 2015 ; Vol. 31, No. 3. pp. 153-157.
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T1 - Evaluation of the mechanical properties of the anterior lens capsule following femtosecond laser capsulotomy at different pulse energy settings

AU - Sándor, Gábor L.

AU - Kiss, Zoltán

AU - Bocskai, Zoltán I.

AU - Kolev, K.

AU - Takács, A.

AU - Juhász, Éva

AU - Kránitz, Kinga

AU - Tóth, Gábor

AU - Gyenes, Andrea

AU - Bojtár, Imre

AU - Juhász, Tibor

AU - Nagy, Zoltán Z.

PY - 2015/3/1

Y1 - 2015/3/1

N2 - PURPOSE: To evaluate and compare the mechanical properties of anterior capsule opening performed with femtosecond laser capsulotomy at different energy settings in ex vivo porcine anterior lens capsule specimens. METHODS: Twenty-five fresh porcine eyes per group were included in the study. Femtosecond laser capsulotomy was performed with three different pulse energy levels: 2 μJ (low energy group), 5 μJ (intermediate energy group), and 10 μJ (high energy group). The capsule openings were stretched with universal testing equipment until they ruptured. The morphologic profile of the cut capsule edges was evaluated using scanning electron microscopy. RESULTS: The high energy group had significantly lower rupture force (108 ± 14 mN) compared to the intermediate energy group (118 ± 10 mN) (P <.05) and low energy group (119 ± 11 mN) (P <.05), but the difference between the intermediate energy and low energy groups was not significant (P = .9479). The high energy group had significantly lower circumference stretching ratio (144% ± 3%) compared to the intermediate energy group (148%± 3%) (P <.05) and low energy group (148% ± 3%) (P <.05), but the difference between the intermediate energy group and low energy group was not significant (P = .9985). Scanning electron microscopy images showed that the edge was only serrated with low and intermediate energy, but additional signs of collagen melting and denaturation were observed at high energy. CONCLUSIONS: Anterior capsule openings created at a high energy level were slightly weaker and less extensible than those created at low or intermediate levels, possibly due to the increased thermal effect of photodisruption.

AB - PURPOSE: To evaluate and compare the mechanical properties of anterior capsule opening performed with femtosecond laser capsulotomy at different energy settings in ex vivo porcine anterior lens capsule specimens. METHODS: Twenty-five fresh porcine eyes per group were included in the study. Femtosecond laser capsulotomy was performed with three different pulse energy levels: 2 μJ (low energy group), 5 μJ (intermediate energy group), and 10 μJ (high energy group). The capsule openings were stretched with universal testing equipment until they ruptured. The morphologic profile of the cut capsule edges was evaluated using scanning electron microscopy. RESULTS: The high energy group had significantly lower rupture force (108 ± 14 mN) compared to the intermediate energy group (118 ± 10 mN) (P <.05) and low energy group (119 ± 11 mN) (P <.05), but the difference between the intermediate energy and low energy groups was not significant (P = .9479). The high energy group had significantly lower circumference stretching ratio (144% ± 3%) compared to the intermediate energy group (148%± 3%) (P <.05) and low energy group (148% ± 3%) (P <.05), but the difference between the intermediate energy group and low energy group was not significant (P = .9985). Scanning electron microscopy images showed that the edge was only serrated with low and intermediate energy, but additional signs of collagen melting and denaturation were observed at high energy. CONCLUSIONS: Anterior capsule openings created at a high energy level were slightly weaker and less extensible than those created at low or intermediate levels, possibly due to the increased thermal effect of photodisruption.

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