Evaluation of substitutes for bone: Comparison of microradiographic and histological assessments

M. Thorwarth, F. Wehrhan, S. Srour, S. Schultze-Mosgau, E. Felszeghy, R. D. Bader, K. A. Schlegel

Research output: Contribution to journalArticle

18 Citations (Scopus)


We created defects of standard size in the frontal bones of adult pigs and filled them with four different materials. On six occasions (at 1, 2, 4, 8, 12, and 26 weeks), samples were harvested, and evaluated by computing microradiographic images. We examined the specimens histologically as controls. After insertion of anorganic materials, microradiographic evaluation was easy and precise, and there were no significant differences between them and the histological controls (p = 0.2). A quantitative evaluation of chemically sterilised bone by computer was not possible for more than 4 weeks.

Original languageEnglish
Pages (from-to)41-47
Number of pages7
JournalBritish Journal of Oral and Maxillofacial Surgery
Issue number1
Publication statusPublished - Jan 1 2007



  • Animal model
  • Anorganic bone matrix
  • Bone regeneration
  • Chemically sterilised bone
  • Microradiographic evaluation
  • Phycogenic hydroxyapatite
  • Prospective study

ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

Cite this