Evaluation of GnRH treatment 12 days after AI in the reproductive performance of dairy cows

O. Szenci, Edit Takács, José Sulon, Noelita Melo de Sousa, Jean Francois Beckers

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The objective of this study was to evaluate the effects of GnRH administered at Day 12 post-AI on the reproductive performance of dairy cows. Holstein-Friesian dairy cows (n = 103) on a large Hungarian dairy farm were allocated randomly to treated (n = 54) or control (n = 49) groups. Twelve days after AI, treated cows received a GnRH agonist i.m., while the control group received a placebo (physiological saline). Progesterone radioimmunoassay was used to determine the correct timing of artificial insemination (Day 0) and the incidence of luteal insufficiency on Day 12. Ultrasonography and radioimmunoassay for pregnancy-associated glycoprotein were used to detect pregnancy and late embryonic/fetal mortality between Days 32 and 55 after AI. Three cows from each group were inseminated when progesterone concentrations were >1.0 ng/mL, and six cows (four from the treated and two from the control group) had luteal insufficiency (progesterone <1.0 ng/mL) on Day 12. Late embryonic/fetal mortality occurred in three treated cows and in two control cows. When these cows were removed from the model, calving rates after first service were 59.6% (28/47) and 59.1% (26/44) for treated and control cows, respectively (P > 0.05). There was no significant difference between treated and control cows when they were inseminated before or after Day 100 from calving. In summary, administration of a GnRH agonist on Day 12 after AI did not improve reproductive performance in dairy cows. However, our approach may be used for the field evaluation of different treatment protocols.

Original languageEnglish
Pages (from-to)1811-1815
Number of pages5
JournalTheriogenology
Volume66
Issue number8
DOIs
Publication statusPublished - Nov 2006

Fingerprint

Gonadotropin-Releasing Hormone
Progesterone
reproductive performance
dairy cows
Corpus Luteum
cows
progesterone
Radioimmunoassay
radioimmunoassays
corpus luteum
agonists
Fetal Mortality
Pregnancy
Artificial Insemination
Control Groups
pregnancy
Clinical Protocols
Ultrasonography
Glycoproteins
Therapeutics

Keywords

  • Dairy cow
  • Day 12 after AI
  • GnRH agonist
  • Luteal insufficiency
  • Timing of AI

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Evaluation of GnRH treatment 12 days after AI in the reproductive performance of dairy cows. / Szenci, O.; Takács, Edit; Sulon, José; Sousa, Noelita Melo de; Beckers, Jean Francois.

In: Theriogenology, Vol. 66, No. 8, 11.2006, p. 1811-1815.

Research output: Contribution to journalArticle

Szenci, O. ; Takács, Edit ; Sulon, José ; Sousa, Noelita Melo de ; Beckers, Jean Francois. / Evaluation of GnRH treatment 12 days after AI in the reproductive performance of dairy cows. In: Theriogenology. 2006 ; Vol. 66, No. 8. pp. 1811-1815.
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