Evaluation of enhanced corneal compensation in scanning laser polarimetry: Comparison with variable corneal compensation on human eyes undergoing LASIK

Márta Tóth, G. Holló

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Purpose: To investigate the potential advantages of an enhanced corneal compensation algorithm (ECC) compared with variable corneal compensation (VCC), in scanning laser polarimetry. Methods: One eye of 15 healthy ametropic subjects was imaged immediately before and 7 days after uncomplicated LASIK surgery. Anterior segment birefringence was assessed at each measurement session. For post-LASIK calculations, either actual post-LASIK corneal retardation (VCC and ECC groups), or the pre-LASIK corneal retardation (VCC* and ECC* groups) was used. Results: The typical scan score-value was higher for ECC both before and after LASIK (P <0.01), and it was not influenced by LASIK in either compensation method. Both the axis and the magnitude of corneal birefringence altered after LASIK (P <0.01). After LASIK, with VCC* all eyes showed uncompensated birefringence, but with ECC* none did. LASIK had no effect on retinal nerve fiber layer measurements in VCC and ECC methods. In VCC* the LASIK-induced retinal nerve fiber layer thickness change was significant (P <0.01) in the temporal, superior, and nasal quadrants. After LASIK, the number of significantly altered sectors along the TSNIT plot showed no difference when comparing VCC and ECC, VCC and ECC*, or ECC and ECC*. In contrast, significantly more sectors were altered in VCC* than in either VCC or ECC* (P <0.001). Conclusions: The new ECC software is more effective than VCC in neutralization of atypical polarization pattern and the uncompensated corneal retardation.

Original languageEnglish
Pages (from-to)53-59
Number of pages7
JournalJournal of Glaucoma
Volume15
Issue number1
DOIs
Publication statusPublished - Feb 2006

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Scanning Laser Polarimetry
Laser In Situ Keratomileusis
Birefringence
Nerve Fibers
Nose

Keywords

  • Glaucoma
  • LASIK
  • Retinal nerve fiber layer
  • Scanning laser polarimetry

ASJC Scopus subject areas

  • Ophthalmology

Cite this

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title = "Evaluation of enhanced corneal compensation in scanning laser polarimetry: Comparison with variable corneal compensation on human eyes undergoing LASIK",
abstract = "Purpose: To investigate the potential advantages of an enhanced corneal compensation algorithm (ECC) compared with variable corneal compensation (VCC), in scanning laser polarimetry. Methods: One eye of 15 healthy ametropic subjects was imaged immediately before and 7 days after uncomplicated LASIK surgery. Anterior segment birefringence was assessed at each measurement session. For post-LASIK calculations, either actual post-LASIK corneal retardation (VCC and ECC groups), or the pre-LASIK corneal retardation (VCC* and ECC* groups) was used. Results: The typical scan score-value was higher for ECC both before and after LASIK (P <0.01), and it was not influenced by LASIK in either compensation method. Both the axis and the magnitude of corneal birefringence altered after LASIK (P <0.01). After LASIK, with VCC* all eyes showed uncompensated birefringence, but with ECC* none did. LASIK had no effect on retinal nerve fiber layer measurements in VCC and ECC methods. In VCC* the LASIK-induced retinal nerve fiber layer thickness change was significant (P <0.01) in the temporal, superior, and nasal quadrants. After LASIK, the number of significantly altered sectors along the TSNIT plot showed no difference when comparing VCC and ECC, VCC and ECC*, or ECC and ECC*. In contrast, significantly more sectors were altered in VCC* than in either VCC or ECC* (P <0.001). Conclusions: The new ECC software is more effective than VCC in neutralization of atypical polarization pattern and the uncompensated corneal retardation.",
keywords = "Glaucoma, LASIK, Retinal nerve fiber layer, Scanning laser polarimetry",
author = "M{\'a}rta T{\'o}th and G. Holl{\'o}",
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T2 - Comparison with variable corneal compensation on human eyes undergoing LASIK

AU - Tóth, Márta

AU - Holló, G.

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N2 - Purpose: To investigate the potential advantages of an enhanced corneal compensation algorithm (ECC) compared with variable corneal compensation (VCC), in scanning laser polarimetry. Methods: One eye of 15 healthy ametropic subjects was imaged immediately before and 7 days after uncomplicated LASIK surgery. Anterior segment birefringence was assessed at each measurement session. For post-LASIK calculations, either actual post-LASIK corneal retardation (VCC and ECC groups), or the pre-LASIK corneal retardation (VCC* and ECC* groups) was used. Results: The typical scan score-value was higher for ECC both before and after LASIK (P <0.01), and it was not influenced by LASIK in either compensation method. Both the axis and the magnitude of corneal birefringence altered after LASIK (P <0.01). After LASIK, with VCC* all eyes showed uncompensated birefringence, but with ECC* none did. LASIK had no effect on retinal nerve fiber layer measurements in VCC and ECC methods. In VCC* the LASIK-induced retinal nerve fiber layer thickness change was significant (P <0.01) in the temporal, superior, and nasal quadrants. After LASIK, the number of significantly altered sectors along the TSNIT plot showed no difference when comparing VCC and ECC, VCC and ECC*, or ECC and ECC*. In contrast, significantly more sectors were altered in VCC* than in either VCC or ECC* (P <0.001). Conclusions: The new ECC software is more effective than VCC in neutralization of atypical polarization pattern and the uncompensated corneal retardation.

AB - Purpose: To investigate the potential advantages of an enhanced corneal compensation algorithm (ECC) compared with variable corneal compensation (VCC), in scanning laser polarimetry. Methods: One eye of 15 healthy ametropic subjects was imaged immediately before and 7 days after uncomplicated LASIK surgery. Anterior segment birefringence was assessed at each measurement session. For post-LASIK calculations, either actual post-LASIK corneal retardation (VCC and ECC groups), or the pre-LASIK corneal retardation (VCC* and ECC* groups) was used. Results: The typical scan score-value was higher for ECC both before and after LASIK (P <0.01), and it was not influenced by LASIK in either compensation method. Both the axis and the magnitude of corneal birefringence altered after LASIK (P <0.01). After LASIK, with VCC* all eyes showed uncompensated birefringence, but with ECC* none did. LASIK had no effect on retinal nerve fiber layer measurements in VCC and ECC methods. In VCC* the LASIK-induced retinal nerve fiber layer thickness change was significant (P <0.01) in the temporal, superior, and nasal quadrants. After LASIK, the number of significantly altered sectors along the TSNIT plot showed no difference when comparing VCC and ECC, VCC and ECC*, or ECC and ECC*. In contrast, significantly more sectors were altered in VCC* than in either VCC or ECC* (P <0.001). Conclusions: The new ECC software is more effective than VCC in neutralization of atypical polarization pattern and the uncompensated corneal retardation.

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