A kapszulás endoszkópia diagnosztikus értékének és klinikai kihatásának vizsgálata tisztázatlan eredetu gasztrointesztinális vérzésekben

Translated title of the contribution: Evaluation of diagnostic yield and clinical impact of capsule endoscopy in patients with obscure gastrointestinal bleeding

Márta Kovács, Artur Németh, Péter Pák, Andrea Uhlyarik, Gábor Pák, I. Rácz

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background and aims: The major indication of small owel capsule endoscopy is the diagnostics of obscure gastrointestinal bleeding. The present retrospective study was aimed to analyze the diagnostic yield, positive and negative predictive values and clinical impact of capsule endoscopy in patients with obscure gastrointestinal bleeding. Patients and methods: During a 36 month period at two workplaces 66 capsule endoscopy studies were performed in 62 patients with gastrointestinal bleeding who had undergone non-diagnostic upper endoscopy and colonoscopy. Capsule video recordings were evaluated by two investigators at both workplaces. Capsule endoscopy findings were divided into 3 groups according to the bleeding source: definitive bleeding source (48 patients), uncertain bleeding potential (5 patients), and negative finding (8 patient). Patients after capsule endoscopy were followed-up until a mean of 20 (1-41) months. Results: A definitive small bowel bleeding source was detected in 78.7% of the cases studied by capsule endoscopy. Definitive bleeding sources included angiodysplasia (28 cases), small bowel Crohn's disease (5 cases), small bowel tumor (5 cases), small bowel stenosis (2 cases), NSAID therapy related ulcer (1 case), non-specific inflammation (1 case) and helminthiasis (1 case) respectively. The positive and negative predictive values of capsule endoscopy studies were 95.8% and 84.6% respectively. In cases with definitive bleeding sources 72% of patients received therapy in accordance with capsule endoscopy findings (surgery in 18 patients, medical treatment modification in 16 patients, chemoembolisation in 1 patient). During the follow-up period 17.7% of the patients had rebleeding. Condusions: Capsule endoscopy is a useful and effective diagnostic method in cases with obscure gastrointestinal bleeding. Effective therapy may be introduced in accordance witb the majority of positive capsule endoscopy results.

Original languageHungarian
Pages (from-to)1827-1833
Number of pages7
JournalOrvosi Hetilap
Volume147
Issue number38
Publication statusPublished - Sep 24 2006

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Capsule Endoscopy
Hemorrhage
Workplace
Angiodysplasia
Helminthiasis
Video Recording
Non-Steroidal Anti-Inflammatory Agents
Colonoscopy
Therapeutics
Crohn Disease
Endoscopy
Ulcer
Capsules
Pathologic Constriction

ASJC Scopus subject areas

  • Medicine(all)

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A kapszulás endoszkópia diagnosztikus értékének és klinikai kihatásának vizsgálata tisztázatlan eredetu gasztrointesztinális vérzésekben. / Kovács, Márta; Németh, Artur; Pák, Péter; Uhlyarik, Andrea; Pák, Gábor; Rácz, I.

In: Orvosi Hetilap, Vol. 147, No. 38, 24.09.2006, p. 1827-1833.

Research output: Contribution to journalArticle

Kovács, Márta ; Németh, Artur ; Pák, Péter ; Uhlyarik, Andrea ; Pák, Gábor ; Rácz, I. / A kapszulás endoszkópia diagnosztikus értékének és klinikai kihatásának vizsgálata tisztázatlan eredetu gasztrointesztinális vérzésekben. In: Orvosi Hetilap. 2006 ; Vol. 147, No. 38. pp. 1827-1833.
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abstract = "Background and aims: The major indication of small owel capsule endoscopy is the diagnostics of obscure gastrointestinal bleeding. The present retrospective study was aimed to analyze the diagnostic yield, positive and negative predictive values and clinical impact of capsule endoscopy in patients with obscure gastrointestinal bleeding. Patients and methods: During a 36 month period at two workplaces 66 capsule endoscopy studies were performed in 62 patients with gastrointestinal bleeding who had undergone non-diagnostic upper endoscopy and colonoscopy. Capsule video recordings were evaluated by two investigators at both workplaces. Capsule endoscopy findings were divided into 3 groups according to the bleeding source: definitive bleeding source (48 patients), uncertain bleeding potential (5 patients), and negative finding (8 patient). Patients after capsule endoscopy were followed-up until a mean of 20 (1-41) months. Results: A definitive small bowel bleeding source was detected in 78.7{\%} of the cases studied by capsule endoscopy. Definitive bleeding sources included angiodysplasia (28 cases), small bowel Crohn's disease (5 cases), small bowel tumor (5 cases), small bowel stenosis (2 cases), NSAID therapy related ulcer (1 case), non-specific inflammation (1 case) and helminthiasis (1 case) respectively. The positive and negative predictive values of capsule endoscopy studies were 95.8{\%} and 84.6{\%} respectively. In cases with definitive bleeding sources 72{\%} of patients received therapy in accordance with capsule endoscopy findings (surgery in 18 patients, medical treatment modification in 16 patients, chemoembolisation in 1 patient). During the follow-up period 17.7{\%} of the patients had rebleeding. Condusions: Capsule endoscopy is a useful and effective diagnostic method in cases with obscure gastrointestinal bleeding. Effective therapy may be introduced in accordance witb the majority of positive capsule endoscopy results.",
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AB - Background and aims: The major indication of small owel capsule endoscopy is the diagnostics of obscure gastrointestinal bleeding. The present retrospective study was aimed to analyze the diagnostic yield, positive and negative predictive values and clinical impact of capsule endoscopy in patients with obscure gastrointestinal bleeding. Patients and methods: During a 36 month period at two workplaces 66 capsule endoscopy studies were performed in 62 patients with gastrointestinal bleeding who had undergone non-diagnostic upper endoscopy and colonoscopy. Capsule video recordings were evaluated by two investigators at both workplaces. Capsule endoscopy findings were divided into 3 groups according to the bleeding source: definitive bleeding source (48 patients), uncertain bleeding potential (5 patients), and negative finding (8 patient). Patients after capsule endoscopy were followed-up until a mean of 20 (1-41) months. Results: A definitive small bowel bleeding source was detected in 78.7% of the cases studied by capsule endoscopy. Definitive bleeding sources included angiodysplasia (28 cases), small bowel Crohn's disease (5 cases), small bowel tumor (5 cases), small bowel stenosis (2 cases), NSAID therapy related ulcer (1 case), non-specific inflammation (1 case) and helminthiasis (1 case) respectively. The positive and negative predictive values of capsule endoscopy studies were 95.8% and 84.6% respectively. In cases with definitive bleeding sources 72% of patients received therapy in accordance with capsule endoscopy findings (surgery in 18 patients, medical treatment modification in 16 patients, chemoembolisation in 1 patient). During the follow-up period 17.7% of the patients had rebleeding. Condusions: Capsule endoscopy is a useful and effective diagnostic method in cases with obscure gastrointestinal bleeding. Effective therapy may be introduced in accordance witb the majority of positive capsule endoscopy results.

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