EURRECA-Estimating Zinc Requirements for Deriving Dietary Reference Values

Nicola M. Lowe, Fiona C. Dykes, Anna Louise Skinner, Sujata Patel, Marisol Warthon-Medina, Tamás Decsi, Katalin Fekete, Olga W. Souverein, Carla Dullemeijer, Adriënne E. Cavelaars, Lluis Serra-Majem, Mariela Nissensohn, Silvia Bel, Luis A. Moreno, Maria Hermoso, Christiane Vollhardt, Cristiana Berti, Irene Cetin, Mirjana Gurinovic, Romana NovakovicLinda J. Harvey, Rachel Collings, Victoria Hall-Moran

Research output: Contribution to journalReview article

29 Citations (Scopus)


Zinc was selected as a priority micronutrient for EURRECA, because there is significant heterogeneity in the Dietary Reference Values (DRVs) across Europe. In addition, the prevalence of inadequate zinc intakes was thought to be high among all population groups worldwide, and the public health concern is considerable. In accordance with the EURRECA consortium principles and protocols, a series of literature reviews were undertaken in order to develop best practice guidelines for assessing dietary zinc intake and zinc status. These were incorporated into subsequent literature search strategies and protocols for studies investigating the relationships between zinc intake, status and health, as well as studies relating to the factorial approach (including bioavailability) for setting dietary recommendations. EMBASE (Ovid), Cochrane Library CENTRAL, and MEDLINE (Ovid) databases were searched for studies published up to February 2010 and collated into a series of Endnote databases that are available for the use of future DRV panels. Meta-analyses of data extracted from these publications were performed where possible in order to address specific questions relating to factors affecting dietary recommendations. This review has highlighted the need for more high quality studies to address gaps in current knowledge, in particular the continued search for a reliable biomarker of zinc status and the influence of genetic polymorphisms on individual dietary requirements. In addition, there is a need to further develop models of the effect of dietary inhibitors of zinc absorption and their impact on population dietary zinc requirements.

Original languageEnglish
Pages (from-to)1110-1123
Number of pages14
JournalCritical Reviews in Food Science and Nutrition
Issue number10
Publication statusPublished - Sep 9 2013


  • Zinc
  • dietary recommendations
  • systematic review
  • zinc bioavailability
  • zinc intake
  • zinc requirements
  • zinc status

ASJC Scopus subject areas

  • Food Science
  • Industrial and Manufacturing Engineering

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    Lowe, N. M., Dykes, F. C., Skinner, A. L., Patel, S., Warthon-Medina, M., Decsi, T., Fekete, K., Souverein, O. W., Dullemeijer, C., Cavelaars, A. E., Serra-Majem, L., Nissensohn, M., Bel, S., Moreno, L. A., Hermoso, M., Vollhardt, C., Berti, C., Cetin, I., Gurinovic, M., ... Hall-Moran, V. (2013). EURRECA-Estimating Zinc Requirements for Deriving Dietary Reference Values. Critical Reviews in Food Science and Nutrition, 53(10), 1110-1123.