Esterification of amino acids to n-butyl and isobutyl esters in aqueous solutions for their gas chromatographic analysis

I. Molnár-Perl, V. Fábián-Vonsik, M. Szakács-Pintér

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7 Citations (Scopus)


Amino acids have been esterified with n-butanol and isobutanol in the presence of perchloric acid. It has been established that in the concentration range of [H2O]/[n-BuOH]=0.10-0.40 esterification can be utilized for the determination of alanine, glycine, valine, leucine, proline, methionine, aspartic acid, phenylalanine, tyrosine, glutamic acid, lysine, arginine, histidine and cystine. In the case of [H2O]/[i-BuOH] =0.05-0.20 the esterification yield decreases from 100% to 70%, in proportion to the water content.

Original languageEnglish
Pages (from-to)652-656
Number of pages5
Issue number11
Publication statusPublished - Nov 1 1985



  • Esterification in aqueous solution
  • Gas chromatography
  • n-Butyl esters of amino acids

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry
  • Organic Chemistry

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