Essential oils in the treatment of respiratory tract diseases highlighting their role in bacterial infections and their anti-inflammatory action

A review

G. Horváth, Kamilla Ács

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The appearance of multidrug resistant bacteria and growing antibiotic resistance is leading to a continuous need for discovering new drugs and alternative treatments against infections. The investigation of the antibacterial effect of essential oils (EOs), which are commonly used nowadays in cosmetics, health care, traditional medicine and food industry, could be one of the promising solutions for this worldwide problem. EOs have a complex mode of action due to their multiple composition. Respiratory tract diseases (RTDs) associated with bacterial infection and inflammation affect a large number of people from every age group worldwide. Because of volatility, EOs can easily reach the upper and lower parts of the respiratory tract via inhalation. Moreover, due to their antimicrobial and anti-inflammatory potency, they offer an effective treatment in respiratory tract infections (RTIs). The purpose of this review is to describe the most frequently developing infections of the upper and lower respiratory tract and to show methods used for the determination of the antibacterial activity of EOs by gaseous contact. The mode of action of EOs on bacterial cells and their anti-inflammatory action are also discussed. Results coming from recently performed in vivo animal studies as well as human trials are also reported. Patents deal with the role of EOs and their volatile constituents in the treatment of RTIs are also introduced. On the whole, this review aimed at showing EOs as potential antimicrobials and as anti-inflammatory agents to alleviate symptoms and signs of RTDs including RTIs.

Original languageEnglish
Pages (from-to)331-341
Number of pages11
JournalFlavour and Fragrance Journal
Volume30
Issue number5
DOIs
Publication statusPublished - Sep 1 2015

Fingerprint

Respiratory Tract Diseases
Pulmonary diseases
Volatile Oils
bacterial infections
Bacterial Infections
respiratory tract diseases
essential oils
Anti-Inflammatory Agents
Respiratory Tract Infections
respiratory system
Therapeutics
mechanism of action
anti-infective agents
anti-inflammatory agents
Volatilization
Patents
Cosmetics
new drugs
traditional foods
Food Industry

Keywords

  • Antimicrobial activity
  • Essential oil
  • Human trial
  • in vivo study
  • Patent
  • Respiratory tract infections
  • Vapour phase

ASJC Scopus subject areas

  • Food Science
  • Chemistry(all)

Cite this

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abstract = "The appearance of multidrug resistant bacteria and growing antibiotic resistance is leading to a continuous need for discovering new drugs and alternative treatments against infections. The investigation of the antibacterial effect of essential oils (EOs), which are commonly used nowadays in cosmetics, health care, traditional medicine and food industry, could be one of the promising solutions for this worldwide problem. EOs have a complex mode of action due to their multiple composition. Respiratory tract diseases (RTDs) associated with bacterial infection and inflammation affect a large number of people from every age group worldwide. Because of volatility, EOs can easily reach the upper and lower parts of the respiratory tract via inhalation. Moreover, due to their antimicrobial and anti-inflammatory potency, they offer an effective treatment in respiratory tract infections (RTIs). The purpose of this review is to describe the most frequently developing infections of the upper and lower respiratory tract and to show methods used for the determination of the antibacterial activity of EOs by gaseous contact. The mode of action of EOs on bacterial cells and their anti-inflammatory action are also discussed. Results coming from recently performed in vivo animal studies as well as human trials are also reported. Patents deal with the role of EOs and their volatile constituents in the treatment of RTIs are also introduced. On the whole, this review aimed at showing EOs as potential antimicrobials and as anti-inflammatory agents to alleviate symptoms and signs of RTDs including RTIs.",
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