Essential fatty acids in full term infants fed breast milk or formula

T. Decsi, I. Thiel, B. Koletzko

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

To determine the biochemical effects of the fatty acid composition of plasma lipids, two groups of 10 healthy full term infants who were either exclusively breast fed or received a formula with similar contents of linoleic and α linolenic acids, but without long chain polyunsaturated (LCP) fatty acids, were studied prospectively. Plasma phospholipid, triglyceride, and sterol ester fatty acids were determined at the age of 2, 4, and 8 weeks by high resolution capillary gas chromatography. Breast fed infants maintained stable LCP fatty acid concentrations throughout the study. Formula fed infants had significantly lower median values of arachidonic acid (AA) at the ages of 2 (6.9 v 9.5% wt/wt) and 4 weeks (5.9 v 7.9%) and docosahexaenoic acid (DHA) at the ages of 4 (1.1 v 1.7%) and 8 weeks (1.0 v 1.7%) in plasma phospholipids. Median AA values in triglycerides were also significantly lower in the infants receiving formula at the ages of 2 (0.4 v 0.6%) and 4 weeks (0.3 v 0.6%). It is concluded that formula fed full term infants are unable to match the ω-3 and ω-6 LCP status of breast fed full term infants until at least two months after birth.

Original languageEnglish
JournalArchives of Disease in Childhood
Volume72
Issue number1 SUPPL.
Publication statusPublished - 1995

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Essential Fatty Acids
Human Milk
Infant Formula
Breast
Unsaturated Fatty Acids
Arachidonic Acid
Phospholipids
Triglycerides
Fatty Acids
Linolenic Acids
Linoleic Acids
Docosahexaenoic Acids
Sterols
Gas Chromatography
Esters
Parturition
Lipids

Keywords

  • Breast milk
  • Essential fatty acids
  • Formula
  • Term infants

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Essential fatty acids in full term infants fed breast milk or formula. / Decsi, T.; Thiel, I.; Koletzko, B.

In: Archives of Disease in Childhood, Vol. 72, No. 1 SUPPL., 1995.

Research output: Contribution to journalArticle

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