Esophageal tonsil

A novel gut-associated lymphoid organ

I. Oláh, N. Nagy, A. Magyar, V. Palya

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

The esophageal tonsil of the chicken is a novel, significant element of the gut-associated lymphoid tissue (GALT). Its stable location and histological organization fulfills the meaning of the term "tonsil." The six-to-eight-isolated tonsillar units are located at the border of the esophagus and the proventriculus. The number of tonsillar units is identical with that of the esophageal folds. Each tonsillar unit consists of a crypt lined by lymphoepithelium and surrounded by dense lymphoid tissue, which is organized into T- and B-dependent regions, like peripheral lymphoid organs. The excretory ducts of the mucosal glands of the esophagus are frequently involved in the formation of the lymphoepithelium. The esophageal tonsil is anatomically located cranial to the stomach, unlike the other parts of the GALT. Therefore, it is continuously exposed to undigested environmental antigens, allergens, food, and infectious agents. To develop effective oral vaccines, the existence of the esophageal tonsil has to be taken into account.

Original languageEnglish
Pages (from-to)767-770
Number of pages4
JournalPoultry Science
Volume82
Issue number5
Publication statusPublished - May 2003

Fingerprint

tonsils
digestive system
esophagus
proventriculus
allergens
mouth
stomach
vaccines
chickens
antigens
pathogens
tissues

Keywords

  • Chicken
  • Esophageal tonsil
  • Gut-associated lymphoid tissue
  • Lymphoepithelial tissue

ASJC Scopus subject areas

  • Animal Science and Zoology

Cite this

Esophageal tonsil : A novel gut-associated lymphoid organ. / Oláh, I.; Nagy, N.; Magyar, A.; Palya, V.

In: Poultry Science, Vol. 82, No. 5, 05.2003, p. 767-770.

Research output: Contribution to journalArticle

Oláh, I. ; Nagy, N. ; Magyar, A. ; Palya, V. / Esophageal tonsil : A novel gut-associated lymphoid organ. In: Poultry Science. 2003 ; Vol. 82, No. 5. pp. 767-770.
@article{0a38a4d00cb4470eae336eaf29c5ad01,
title = "Esophageal tonsil: A novel gut-associated lymphoid organ",
abstract = "The esophageal tonsil of the chicken is a novel, significant element of the gut-associated lymphoid tissue (GALT). Its stable location and histological organization fulfills the meaning of the term {"}tonsil.{"} The six-to-eight-isolated tonsillar units are located at the border of the esophagus and the proventriculus. The number of tonsillar units is identical with that of the esophageal folds. Each tonsillar unit consists of a crypt lined by lymphoepithelium and surrounded by dense lymphoid tissue, which is organized into T- and B-dependent regions, like peripheral lymphoid organs. The excretory ducts of the mucosal glands of the esophagus are frequently involved in the formation of the lymphoepithelium. The esophageal tonsil is anatomically located cranial to the stomach, unlike the other parts of the GALT. Therefore, it is continuously exposed to undigested environmental antigens, allergens, food, and infectious agents. To develop effective oral vaccines, the existence of the esophageal tonsil has to be taken into account.",
keywords = "Chicken, Esophageal tonsil, Gut-associated lymphoid tissue, Lymphoepithelial tissue",
author = "I. Ol{\'a}h and N. Nagy and A. Magyar and V. Palya",
year = "2003",
month = "5",
language = "English",
volume = "82",
pages = "767--770",
journal = "Poultry Science",
issn = "0032-5791",
publisher = "Poultry Science Association",
number = "5",

}

TY - JOUR

T1 - Esophageal tonsil

T2 - A novel gut-associated lymphoid organ

AU - Oláh, I.

AU - Nagy, N.

AU - Magyar, A.

AU - Palya, V.

PY - 2003/5

Y1 - 2003/5

N2 - The esophageal tonsil of the chicken is a novel, significant element of the gut-associated lymphoid tissue (GALT). Its stable location and histological organization fulfills the meaning of the term "tonsil." The six-to-eight-isolated tonsillar units are located at the border of the esophagus and the proventriculus. The number of tonsillar units is identical with that of the esophageal folds. Each tonsillar unit consists of a crypt lined by lymphoepithelium and surrounded by dense lymphoid tissue, which is organized into T- and B-dependent regions, like peripheral lymphoid organs. The excretory ducts of the mucosal glands of the esophagus are frequently involved in the formation of the lymphoepithelium. The esophageal tonsil is anatomically located cranial to the stomach, unlike the other parts of the GALT. Therefore, it is continuously exposed to undigested environmental antigens, allergens, food, and infectious agents. To develop effective oral vaccines, the existence of the esophageal tonsil has to be taken into account.

AB - The esophageal tonsil of the chicken is a novel, significant element of the gut-associated lymphoid tissue (GALT). Its stable location and histological organization fulfills the meaning of the term "tonsil." The six-to-eight-isolated tonsillar units are located at the border of the esophagus and the proventriculus. The number of tonsillar units is identical with that of the esophageal folds. Each tonsillar unit consists of a crypt lined by lymphoepithelium and surrounded by dense lymphoid tissue, which is organized into T- and B-dependent regions, like peripheral lymphoid organs. The excretory ducts of the mucosal glands of the esophagus are frequently involved in the formation of the lymphoepithelium. The esophageal tonsil is anatomically located cranial to the stomach, unlike the other parts of the GALT. Therefore, it is continuously exposed to undigested environmental antigens, allergens, food, and infectious agents. To develop effective oral vaccines, the existence of the esophageal tonsil has to be taken into account.

KW - Chicken

KW - Esophageal tonsil

KW - Gut-associated lymphoid tissue

KW - Lymphoepithelial tissue

UR - http://www.scopus.com/inward/record.url?scp=1542311935&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1542311935&partnerID=8YFLogxK

M3 - Article

VL - 82

SP - 767

EP - 770

JO - Poultry Science

JF - Poultry Science

SN - 0032-5791

IS - 5

ER -