Protonation and copper(II), nickel(II) and zinc(II) complex-formation equilibria of 1-(2-aminoethylamino)-1-deoxy-D-galactitol and the solution co-ordination structure of the complexes were investigated by potentiometric titrations, UV/VIS absorption, CD, EPR and 13C NMR spectroscopies in aqueous solution (I = 0.1 mol dm-3, NaClO4; T = 298 K). In acidic media the ethane-1,2-diamine (en) residue dominates the co-ordination for all the metal ions studied, but the spectroscopic results are consistent with weak co-ordination of alcoholic hydroxy group(s). In equimolar solution and at neutral pH, dialkoxide-bridged dimeric species were formed with nickel(II) and copper(II). In case of an excess of galactitol bis- and tris-complexes were also detected. In the latter system metal-promoted deprotonation occured above pH 9 and in this way the second ligand is successively displaced from the co-ordination sphere of copper(II). In the finally formed MLH-2 species the ligand is co-ordinated by two amino and two deprotonated alcoholic hydroxy groups. Nickel(II) formed a ML2H-2 complex in the alkaline pH region. The deprotonation processes of the ZnL2 complex leading also to ML2H-2 took place at almost the same pH as for NiL2. Evidence of the deprotonation of the alcoholic hydroxy groups is available only above pH ≈ 11 in the zinc(II)-containing system.
|Number of pages||6|
|Journal||Journal of the Chemical Society - Dalton Transactions|
|Publication status||Published - Jun 21 1997|
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