Epilepsy and vitamin D

Research output: Contribution to journalReview article

23 Citations (Scopus)

Abstract

Several disorders, both systemic and those of the nervous system, have been linked with vitamin D deficiency. Neurological disorders with a vitamin D link include but are not limited to multiple sclerosis, Alzheimer and Parkinson disease, as well as cerebrovascular disorders. Epilepsy which is the second leading neurological disorder received much less attention. We review evidence supporting a link between vitamin D and epilepsy including those coming from ecological as well as interventional and animal studies. We also assess the literature on the interaction between antiepileptic drugs and vitamin D. Converging evidence indicates a role for vitamin D deficiency in the pathophysiology of epilepsy.

Original languageEnglish
Pages (from-to)387-393
Number of pages7
JournalInternational Journal of Neuroscience
Volume124
Issue number6
DOIs
Publication statusPublished - Jun 2014

Keywords

  • Antiepileptic drugs
  • Neurosteroids
  • Vitamin D deficiency

ASJC Scopus subject areas

  • Neuroscience(all)

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