Epidural malignant lymphomas of the spine: Collected experiences with epidural malignant lymphomas of the spinal canal and their treatment

G. Székely, Z. Miltényi, G. Mezey, Z. Simon, J. Gyarmati, L. Gergely, L. Bognár, A. Illés

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Study design: Retrospective study of 13 patients treated by the authors. Objective: To examine the course of the disease of malignant lymphoma (ML) presenting in the epidural area of the spine. Setting: Department of Neurosurgery, Third Department of Internal Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary. Subjects and methods: The epidural presentation in eight patients was heralded by motor signs (paraparesis and plegia), in one by a lesion of the posterior columns of the spinal cord (ataxia), and in three by pain. One patient was free of complaints and symptoms. The affected epidural area was diagnosed previously by myelography and computerized tomography (CT), and later by magnetic resonance (MR), over the course of which the location was verified as thoracic in eight patients, cervical in one, and lumbar in four. The authors recommended surgical intervention in 9 out of 13 cases, in seven cases of Hodgkin's and six cases of non-Hodgkin's lymphoma. Seven patients were treated for recognized manifestations of malignant lymphoma while six were diagnosed by intraoperative-histological examination. Results and conclusion: The decompression operations for tumors resulted in limited improvement in seven patients (reduction in pain and return of ability to walk). Four patients were not operated on, two of which had significant improvement in their neurological symptoms. Paraparesis remained unchanged in one patient. One patient remained symptom-free. The authors emphasize the importance of interdisciplinary consultation and weighing individual priorities in the indications for operation on epidural ML.

Original languageEnglish
Pages (from-to)278-281
Number of pages4
JournalSpinal Cord
Volume46
Issue number4
DOIs
Publication statusPublished - Apr 11 2008

Fingerprint

Spinal Canal
Lymphoma
Spine
Paraparesis
Therapeutics
Pain
Myelography
Aptitude
Hungary
Neurosurgery
Ataxia
Internal Medicine
Decompression
Hodgkin Disease
Paralysis
Non-Hodgkin's Lymphoma
Spinal Cord
Magnetic Resonance Spectroscopy
Thorax
Referral and Consultation

Keywords

  • Epidural
  • Malignant lymphomas
  • Spine

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Epidural malignant lymphomas of the spine : Collected experiences with epidural malignant lymphomas of the spinal canal and their treatment. / Székely, G.; Miltényi, Z.; Mezey, G.; Simon, Z.; Gyarmati, J.; Gergely, L.; Bognár, L.; Illés, A.

In: Spinal Cord, Vol. 46, No. 4, 11.04.2008, p. 278-281.

Research output: Contribution to journalArticle

@article{2811cc18956b4ffd8f0ed6be4afeeeb8,
title = "Epidural malignant lymphomas of the spine: Collected experiences with epidural malignant lymphomas of the spinal canal and their treatment",
abstract = "Study design: Retrospective study of 13 patients treated by the authors. Objective: To examine the course of the disease of malignant lymphoma (ML) presenting in the epidural area of the spine. Setting: Department of Neurosurgery, Third Department of Internal Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary. Subjects and methods: The epidural presentation in eight patients was heralded by motor signs (paraparesis and plegia), in one by a lesion of the posterior columns of the spinal cord (ataxia), and in three by pain. One patient was free of complaints and symptoms. The affected epidural area was diagnosed previously by myelography and computerized tomography (CT), and later by magnetic resonance (MR), over the course of which the location was verified as thoracic in eight patients, cervical in one, and lumbar in four. The authors recommended surgical intervention in 9 out of 13 cases, in seven cases of Hodgkin's and six cases of non-Hodgkin's lymphoma. Seven patients were treated for recognized manifestations of malignant lymphoma while six were diagnosed by intraoperative-histological examination. Results and conclusion: The decompression operations for tumors resulted in limited improvement in seven patients (reduction in pain and return of ability to walk). Four patients were not operated on, two of which had significant improvement in their neurological symptoms. Paraparesis remained unchanged in one patient. One patient remained symptom-free. The authors emphasize the importance of interdisciplinary consultation and weighing individual priorities in the indications for operation on epidural ML.",
keywords = "Epidural, Malignant lymphomas, Spine",
author = "G. Sz{\'e}kely and Z. Milt{\'e}nyi and G. Mezey and Z. Simon and J. Gyarmati and L. Gergely and L. Bogn{\'a}r and A. Ill{\'e}s",
year = "2008",
month = "4",
day = "11",
doi = "10.1038/sj.sc.3102124",
language = "English",
volume = "46",
pages = "278--281",
journal = "Spinal Cord",
issn = "1362-4393",
publisher = "Nature Publishing Group",
number = "4",

}

TY - JOUR

T1 - Epidural malignant lymphomas of the spine

T2 - Collected experiences with epidural malignant lymphomas of the spinal canal and their treatment

AU - Székely, G.

AU - Miltényi, Z.

AU - Mezey, G.

AU - Simon, Z.

AU - Gyarmati, J.

AU - Gergely, L.

AU - Bognár, L.

AU - Illés, A.

PY - 2008/4/11

Y1 - 2008/4/11

N2 - Study design: Retrospective study of 13 patients treated by the authors. Objective: To examine the course of the disease of malignant lymphoma (ML) presenting in the epidural area of the spine. Setting: Department of Neurosurgery, Third Department of Internal Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary. Subjects and methods: The epidural presentation in eight patients was heralded by motor signs (paraparesis and plegia), in one by a lesion of the posterior columns of the spinal cord (ataxia), and in three by pain. One patient was free of complaints and symptoms. The affected epidural area was diagnosed previously by myelography and computerized tomography (CT), and later by magnetic resonance (MR), over the course of which the location was verified as thoracic in eight patients, cervical in one, and lumbar in four. The authors recommended surgical intervention in 9 out of 13 cases, in seven cases of Hodgkin's and six cases of non-Hodgkin's lymphoma. Seven patients were treated for recognized manifestations of malignant lymphoma while six were diagnosed by intraoperative-histological examination. Results and conclusion: The decompression operations for tumors resulted in limited improvement in seven patients (reduction in pain and return of ability to walk). Four patients were not operated on, two of which had significant improvement in their neurological symptoms. Paraparesis remained unchanged in one patient. One patient remained symptom-free. The authors emphasize the importance of interdisciplinary consultation and weighing individual priorities in the indications for operation on epidural ML.

AB - Study design: Retrospective study of 13 patients treated by the authors. Objective: To examine the course of the disease of malignant lymphoma (ML) presenting in the epidural area of the spine. Setting: Department of Neurosurgery, Third Department of Internal Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary. Subjects and methods: The epidural presentation in eight patients was heralded by motor signs (paraparesis and plegia), in one by a lesion of the posterior columns of the spinal cord (ataxia), and in three by pain. One patient was free of complaints and symptoms. The affected epidural area was diagnosed previously by myelography and computerized tomography (CT), and later by magnetic resonance (MR), over the course of which the location was verified as thoracic in eight patients, cervical in one, and lumbar in four. The authors recommended surgical intervention in 9 out of 13 cases, in seven cases of Hodgkin's and six cases of non-Hodgkin's lymphoma. Seven patients were treated for recognized manifestations of malignant lymphoma while six were diagnosed by intraoperative-histological examination. Results and conclusion: The decompression operations for tumors resulted in limited improvement in seven patients (reduction in pain and return of ability to walk). Four patients were not operated on, two of which had significant improvement in their neurological symptoms. Paraparesis remained unchanged in one patient. One patient remained symptom-free. The authors emphasize the importance of interdisciplinary consultation and weighing individual priorities in the indications for operation on epidural ML.

KW - Epidural

KW - Malignant lymphomas

KW - Spine

UR - http://www.scopus.com/inward/record.url?scp=41849086655&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=41849086655&partnerID=8YFLogxK

U2 - 10.1038/sj.sc.3102124

DO - 10.1038/sj.sc.3102124

M3 - Article

C2 - 17909560

AN - SCOPUS:41849086655

VL - 46

SP - 278

EP - 281

JO - Spinal Cord

JF - Spinal Cord

SN - 1362-4393

IS - 4

ER -