Epidemiology of rotavirus diarrhea in children under 5 years in Northern Cameroon

Valentine Ngum Ndze, Achidi Eric Akum, Gonsu Hortense Kamga, Lyonga Emilia Enjema, Mathew Dioh Esona, K. Bányai, Obama Abena Marie Therese

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background Rotavirus still remains the major cause of diarrhea in children below 5 years. No data on rotavirus epidemiology is available in the Northern regions of Cameroon. We aimed to determine the prevalence of group A rotavirus (RVA) in children below 5 years with diarrhea in two regions of Northern Cameroon (North West and Far North Regions) so as to improve our knowledge on the burden of rotavirus disease for imminent introduction of a rotavirus vaccine. Methods Stool samples were collected during 2010 and 2011 from 390 children below 5 years presenting with diarrhea in four hospitals in Northern Cameroon and were screened for rotavirus group A by reverse transcription-polymerase chain reaction. Results This study revealed that 42.8% of the children below 5 years had group A rotavirus infection, 46.5% in the Far North region while the North West had a prevalence of 33.9%. Of the 252 hospitalized and the 138 outpatient children, 124(49.2%) and 43(31.2%) (P=0.00085), respectively, were positive for group A rotavirus. Children below 24 months were most affected (44.7%), while the age group 49-60 months had the lowest prevalence (25%). The RVA prevalence was 44.6% in the urban and 28.9% in the rural settings of our study. It was observed that the proportion of children with diarrhea who had rotavirus accompanied with fever and vomiting in the outpatient group and inpatient group were 13.0% and 28.6% respectively, P=0.03. Conclusion This study showed high incidence of rotavirus infection especially among hospitalized children in Northern Cameroon, suggesting that rotavirus is a major cause of childhood morbidity and mortality in this area.

Original languageEnglish
Pages (from-to)73
Number of pages1
JournalPan African Medical Journal
Volume11
Publication statusPublished - 2012

Fingerprint

Cameroon
Rotavirus
Diarrhea
Epidemiology
Rotavirus Infections
Outpatients
Rotavirus Vaccines
Hospitalized Child
Reverse Transcription
Vomiting
Inpatients
Fever
Age Groups
Morbidity
Polymerase Chain Reaction
Mortality
Incidence

Keywords

  • Cameroon
  • Children
  • Diarrhea
  • Epidemiology
  • Prevalence
  • Rotavirus

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ndze, V. N., Akum, A. E., Kamga, G. H., Enjema, L. E., Esona, M. D., Bányai, K., & Therese, O. A. M. (2012). Epidemiology of rotavirus diarrhea in children under 5 years in Northern Cameroon. Pan African Medical Journal, 11, 73.

Epidemiology of rotavirus diarrhea in children under 5 years in Northern Cameroon. / Ndze, Valentine Ngum; Akum, Achidi Eric; Kamga, Gonsu Hortense; Enjema, Lyonga Emilia; Esona, Mathew Dioh; Bányai, K.; Therese, Obama Abena Marie.

In: Pan African Medical Journal, Vol. 11, 2012, p. 73.

Research output: Contribution to journalArticle

Ndze, VN, Akum, AE, Kamga, GH, Enjema, LE, Esona, MD, Bányai, K & Therese, OAM 2012, 'Epidemiology of rotavirus diarrhea in children under 5 years in Northern Cameroon', Pan African Medical Journal, vol. 11, pp. 73.
Ndze, Valentine Ngum ; Akum, Achidi Eric ; Kamga, Gonsu Hortense ; Enjema, Lyonga Emilia ; Esona, Mathew Dioh ; Bányai, K. ; Therese, Obama Abena Marie. / Epidemiology of rotavirus diarrhea in children under 5 years in Northern Cameroon. In: Pan African Medical Journal. 2012 ; Vol. 11. pp. 73.
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abstract = "Background Rotavirus still remains the major cause of diarrhea in children below 5 years. No data on rotavirus epidemiology is available in the Northern regions of Cameroon. We aimed to determine the prevalence of group A rotavirus (RVA) in children below 5 years with diarrhea in two regions of Northern Cameroon (North West and Far North Regions) so as to improve our knowledge on the burden of rotavirus disease for imminent introduction of a rotavirus vaccine. Methods Stool samples were collected during 2010 and 2011 from 390 children below 5 years presenting with diarrhea in four hospitals in Northern Cameroon and were screened for rotavirus group A by reverse transcription-polymerase chain reaction. Results This study revealed that 42.8{\%} of the children below 5 years had group A rotavirus infection, 46.5{\%} in the Far North region while the North West had a prevalence of 33.9{\%}. Of the 252 hospitalized and the 138 outpatient children, 124(49.2{\%}) and 43(31.2{\%}) (P=0.00085), respectively, were positive for group A rotavirus. Children below 24 months were most affected (44.7{\%}), while the age group 49-60 months had the lowest prevalence (25{\%}). The RVA prevalence was 44.6{\%} in the urban and 28.9{\%} in the rural settings of our study. It was observed that the proportion of children with diarrhea who had rotavirus accompanied with fever and vomiting in the outpatient group and inpatient group were 13.0{\%} and 28.6{\%} respectively, P=0.03. Conclusion This study showed high incidence of rotavirus infection especially among hospitalized children in Northern Cameroon, suggesting that rotavirus is a major cause of childhood morbidity and mortality in this area.",
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AU - Bányai, K.

AU - Therese, Obama Abena Marie

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N2 - Background Rotavirus still remains the major cause of diarrhea in children below 5 years. No data on rotavirus epidemiology is available in the Northern regions of Cameroon. We aimed to determine the prevalence of group A rotavirus (RVA) in children below 5 years with diarrhea in two regions of Northern Cameroon (North West and Far North Regions) so as to improve our knowledge on the burden of rotavirus disease for imminent introduction of a rotavirus vaccine. Methods Stool samples were collected during 2010 and 2011 from 390 children below 5 years presenting with diarrhea in four hospitals in Northern Cameroon and were screened for rotavirus group A by reverse transcription-polymerase chain reaction. Results This study revealed that 42.8% of the children below 5 years had group A rotavirus infection, 46.5% in the Far North region while the North West had a prevalence of 33.9%. Of the 252 hospitalized and the 138 outpatient children, 124(49.2%) and 43(31.2%) (P=0.00085), respectively, were positive for group A rotavirus. Children below 24 months were most affected (44.7%), while the age group 49-60 months had the lowest prevalence (25%). The RVA prevalence was 44.6% in the urban and 28.9% in the rural settings of our study. It was observed that the proportion of children with diarrhea who had rotavirus accompanied with fever and vomiting in the outpatient group and inpatient group were 13.0% and 28.6% respectively, P=0.03. Conclusion This study showed high incidence of rotavirus infection especially among hospitalized children in Northern Cameroon, suggesting that rotavirus is a major cause of childhood morbidity and mortality in this area.

AB - Background Rotavirus still remains the major cause of diarrhea in children below 5 years. No data on rotavirus epidemiology is available in the Northern regions of Cameroon. We aimed to determine the prevalence of group A rotavirus (RVA) in children below 5 years with diarrhea in two regions of Northern Cameroon (North West and Far North Regions) so as to improve our knowledge on the burden of rotavirus disease for imminent introduction of a rotavirus vaccine. Methods Stool samples were collected during 2010 and 2011 from 390 children below 5 years presenting with diarrhea in four hospitals in Northern Cameroon and were screened for rotavirus group A by reverse transcription-polymerase chain reaction. Results This study revealed that 42.8% of the children below 5 years had group A rotavirus infection, 46.5% in the Far North region while the North West had a prevalence of 33.9%. Of the 252 hospitalized and the 138 outpatient children, 124(49.2%) and 43(31.2%) (P=0.00085), respectively, were positive for group A rotavirus. Children below 24 months were most affected (44.7%), while the age group 49-60 months had the lowest prevalence (25%). The RVA prevalence was 44.6% in the urban and 28.9% in the rural settings of our study. It was observed that the proportion of children with diarrhea who had rotavirus accompanied with fever and vomiting in the outpatient group and inpatient group were 13.0% and 28.6% respectively, P=0.03. Conclusion This study showed high incidence of rotavirus infection especially among hospitalized children in Northern Cameroon, suggesting that rotavirus is a major cause of childhood morbidity and mortality in this area.

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