Epidemiologic characteristics of Helicobacter pylori infection in southeast Hungary

Lenke Bálint, Andrea Tiszai, Gábor Kozák, Ilona Dóczi, Veronika Szekeres, Orsolya Inczefi, Georgina Ollé, Krisztina Helle, Richárd Róka, András Rosztóczy

Research output: Contribution to journalArticle

Abstract

BACKGROUND Epidemiologic studies have revealed a decrease in the prevalence of Helicobacter pylori (H. pylori) infection in Western Europe. AIM To obtain data regarding the prevalence of H. pylori in Csongrád and Békés Counties in Hungary, evaluate the differences in its prevalence between urban and rural areas, and establish factors associated with positive seroprevalence. METHODS One-thousand and one healthy blood donors [male/female: 501/500, mean age: 40 (19–65) years] were enrolled in this study. Subjects were tested for H. pylori IgG antibody positivity via enzyme-linked immunosorbent assay. Subgroup analysis by age, gender, smoking habits, alcohol consumption, and urban vs non-urban residence was also performed. RESULTS The overall seropositivity of H. pylori was 32%. It was higher in males (34.93% vs 29.2%, P = 0.0521) and in rural areas (36.2% vs 27.94%, P = 0.0051). Agricultural/industrial workers were more likely to be positive for infection than office workers (38.35% vs 30.11%, P = 0.0095) and rural subjects in Békés County than those in Csongrád County (43.36% vs 33.33%, P = 0.0015). CONCLUSION Although the prevalence of H. pylori infection decreased in recent decades in Southeast Hungary, it remains high in middle-aged rural populations. Generally accepted risk factors for H. pylori positivity appeared to be valid for the studied population.

Original languageEnglish
Pages (from-to)6365-6372
Number of pages8
JournalWorld journal of gastroenterology
Volume25
Issue number42
DOIs
Publication statusPublished - Nov 14 2019

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Hungary
Helicobacter Infections
Helicobacter pylori
Seroepidemiologic Studies
Rural Population
Blood Donors
Alcohol Drinking
Habits
Epidemiologic Studies
Immunoglobulin G
Smoking
Enzyme-Linked Immunosorbent Assay
Antibodies
Infection
Population

Keywords

  • Central Europe
  • Differences in urban
  • Enzyme-linked immunosorbent assay
  • Epidemiology
  • Healthy volunteers
  • Helicobacter pylori
  • Prevalence
  • Rural population

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Bálint, L., Tiszai, A., Kozák, G., Dóczi, I., Szekeres, V., Inczefi, O., ... Rosztóczy, A. (2019). Epidemiologic characteristics of Helicobacter pylori infection in southeast Hungary. World journal of gastroenterology, 25(42), 6365-6372. https://doi.org/10.3748/wjg.v25.i42.6365

Epidemiologic characteristics of Helicobacter pylori infection in southeast Hungary. / Bálint, Lenke; Tiszai, Andrea; Kozák, Gábor; Dóczi, Ilona; Szekeres, Veronika; Inczefi, Orsolya; Ollé, Georgina; Helle, Krisztina; Róka, Richárd; Rosztóczy, András.

In: World journal of gastroenterology, Vol. 25, No. 42, 14.11.2019, p. 6365-6372.

Research output: Contribution to journalArticle

Bálint, L, Tiszai, A, Kozák, G, Dóczi, I, Szekeres, V, Inczefi, O, Ollé, G, Helle, K, Róka, R & Rosztóczy, A 2019, 'Epidemiologic characteristics of Helicobacter pylori infection in southeast Hungary', World journal of gastroenterology, vol. 25, no. 42, pp. 6365-6372. https://doi.org/10.3748/wjg.v25.i42.6365
Bálint L, Tiszai A, Kozák G, Dóczi I, Szekeres V, Inczefi O et al. Epidemiologic characteristics of Helicobacter pylori infection in southeast Hungary. World journal of gastroenterology. 2019 Nov 14;25(42):6365-6372. https://doi.org/10.3748/wjg.v25.i42.6365
Bálint, Lenke ; Tiszai, Andrea ; Kozák, Gábor ; Dóczi, Ilona ; Szekeres, Veronika ; Inczefi, Orsolya ; Ollé, Georgina ; Helle, Krisztina ; Róka, Richárd ; Rosztóczy, András. / Epidemiologic characteristics of Helicobacter pylori infection in southeast Hungary. In: World journal of gastroenterology. 2019 ; Vol. 25, No. 42. pp. 6365-6372.
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abstract = "BACKGROUND Epidemiologic studies have revealed a decrease in the prevalence of Helicobacter pylori (H. pylori) infection in Western Europe. AIM To obtain data regarding the prevalence of H. pylori in Csongr{\'a}d and B{\'e}k{\'e}s Counties in Hungary, evaluate the differences in its prevalence between urban and rural areas, and establish factors associated with positive seroprevalence. METHODS One-thousand and one healthy blood donors [male/female: 501/500, mean age: 40 (19–65) years] were enrolled in this study. Subjects were tested for H. pylori IgG antibody positivity via enzyme-linked immunosorbent assay. Subgroup analysis by age, gender, smoking habits, alcohol consumption, and urban vs non-urban residence was also performed. RESULTS The overall seropositivity of H. pylori was 32{\%}. It was higher in males (34.93{\%} vs 29.2{\%}, P = 0.0521) and in rural areas (36.2{\%} vs 27.94{\%}, P = 0.0051). Agricultural/industrial workers were more likely to be positive for infection than office workers (38.35{\%} vs 30.11{\%}, P = 0.0095) and rural subjects in B{\'e}k{\'e}s County than those in Csongr{\'a}d County (43.36{\%} vs 33.33{\%}, P = 0.0015). CONCLUSION Although the prevalence of H. pylori infection decreased in recent decades in Southeast Hungary, it remains high in middle-aged rural populations. Generally accepted risk factors for H. pylori positivity appeared to be valid for the studied population.",
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AU - Bálint, Lenke

AU - Tiszai, Andrea

AU - Kozák, Gábor

AU - Dóczi, Ilona

AU - Szekeres, Veronika

AU - Inczefi, Orsolya

AU - Ollé, Georgina

AU - Helle, Krisztina

AU - Róka, Richárd

AU - Rosztóczy, András

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N2 - BACKGROUND Epidemiologic studies have revealed a decrease in the prevalence of Helicobacter pylori (H. pylori) infection in Western Europe. AIM To obtain data regarding the prevalence of H. pylori in Csongrád and Békés Counties in Hungary, evaluate the differences in its prevalence between urban and rural areas, and establish factors associated with positive seroprevalence. METHODS One-thousand and one healthy blood donors [male/female: 501/500, mean age: 40 (19–65) years] were enrolled in this study. Subjects were tested for H. pylori IgG antibody positivity via enzyme-linked immunosorbent assay. Subgroup analysis by age, gender, smoking habits, alcohol consumption, and urban vs non-urban residence was also performed. RESULTS The overall seropositivity of H. pylori was 32%. It was higher in males (34.93% vs 29.2%, P = 0.0521) and in rural areas (36.2% vs 27.94%, P = 0.0051). Agricultural/industrial workers were more likely to be positive for infection than office workers (38.35% vs 30.11%, P = 0.0095) and rural subjects in Békés County than those in Csongrád County (43.36% vs 33.33%, P = 0.0015). CONCLUSION Although the prevalence of H. pylori infection decreased in recent decades in Southeast Hungary, it remains high in middle-aged rural populations. Generally accepted risk factors for H. pylori positivity appeared to be valid for the studied population.

AB - BACKGROUND Epidemiologic studies have revealed a decrease in the prevalence of Helicobacter pylori (H. pylori) infection in Western Europe. AIM To obtain data regarding the prevalence of H. pylori in Csongrád and Békés Counties in Hungary, evaluate the differences in its prevalence between urban and rural areas, and establish factors associated with positive seroprevalence. METHODS One-thousand and one healthy blood donors [male/female: 501/500, mean age: 40 (19–65) years] were enrolled in this study. Subjects were tested for H. pylori IgG antibody positivity via enzyme-linked immunosorbent assay. Subgroup analysis by age, gender, smoking habits, alcohol consumption, and urban vs non-urban residence was also performed. RESULTS The overall seropositivity of H. pylori was 32%. It was higher in males (34.93% vs 29.2%, P = 0.0521) and in rural areas (36.2% vs 27.94%, P = 0.0051). Agricultural/industrial workers were more likely to be positive for infection than office workers (38.35% vs 30.11%, P = 0.0095) and rural subjects in Békés County than those in Csongrád County (43.36% vs 33.33%, P = 0.0015). CONCLUSION Although the prevalence of H. pylori infection decreased in recent decades in Southeast Hungary, it remains high in middle-aged rural populations. Generally accepted risk factors for H. pylori positivity appeared to be valid for the studied population.

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KW - Differences in urban

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