Enzymatic resolution of alicyclic 1,3-amino alcohols in organic media

Mária Péter, Johan Van Der Eycken, Gábor Bernáth, Ferenc Fülöp

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Racemic cis- and trans-2-aminocyclohexane-1-methanol and cis- and trans- 2-amino-4-cyclohexene-1-methanol were resolved via lipase-catalysed O- acylation of their Z derivatives, using vinyl butyrate in different ether solvents. In accordance with the empirical rule, most of the screened lipases preferred the 1S enantiomer.

Original languageEnglish
Pages (from-to)2339-2347
Number of pages9
JournalTetrahedron Asymmetry
Volume9
Issue number13
DOIs
Publication statusPublished - Jul 3 1998

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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