Environmentally controlled dimorphic cycle in a fission yeast

M. Sipiczki, K. Takeo, M. Yamaguchi, S. Yoshida, I. Miklos

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

The fission yeast Schizosaccharomyces pombe shows bipolar growth and is a convenient model for studying cell polarity and polar growth. This paper shows that the related Schiz. japonicus var. japonicus can switch to unipolar growth and can exist in both yeast and mycelial phases. On solid media, the yeast phase is unstable and prone to switch to the mycelial form, which shows unipolar growth by tip elongation. The hyphae can colonize the body of the substrate (true mycelium) or just its surface (pseudo-mycelium). The yeast-to-mycelium transition and the growth of the mycelium are regulated by a nutritional gradient and are associated with extensive vacuolation. The mycelium can convert into arthroconidia or return to the yeast phase in response to environmental changes. These environmentally controlled morphological transitions make Schiz. japonicus var. japonicus an attractive model for the investigation of cell polarity and morphogenesis.

Original languageEnglish
Pages (from-to)1319-1330
Number of pages12
JournalMicrobiology
Volume144
Issue number5
DOIs
Publication statusPublished - May 1998

Keywords

  • Arthrospores
  • Dimorphic transition
  • Polar growth
  • Schizosaccharomyces
  • Vacuolation

ASJC Scopus subject areas

  • Microbiology

Fingerprint Dive into the research topics of 'Environmentally controlled dimorphic cycle in a fission yeast'. Together they form a unique fingerprint.

  • Cite this