Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study

J. Burisch, N. Pedersen, S. Cukovic-Cavka, N. Turk, I. Kaimakliotis, D. Duricova, M. Bortlik, O. Shonová, I. Vind, S. Avnstrøm, N. Thorsgaard, S. Krabbe, V. Andersen, J. F. Dahlerup, J. Kjeldsen, R. Salupere, J. Olsen, K. R. Nielsen, P. Manninen, P. CollinK. H. Katsanos, E. V. Tsianos, K. Ladefoged, L. Lakatos, G. Ragnarsson, E. Björnsson, Y. Bailey, C. O'Morain, D. Schwartz, S. Odes, M. Giannotta, G. Girardin, G. Kiudelis, L. Kupcinskas, S. Turcan, L. Barros, F. Magro, D. Lazar, A. Goldis, I. Nikulina, E. Belousova, D. Martinez-Ares, V. Hernandez, S. Almer, Y. Zhulina, J. Halfvarson, N. Arebi, H. H. Tsai, S. Sebastian, P. Lakatos, E. Langholz, P. Munkholm

Research output: Contribution to journalArticle

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Abstract

Background and Aims: The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe possibly due to changes in environmental factors towards a more "westernised" standard of living. The aim of this study was to investigate differences in exposure to environmental factors prior to diagnosis in Eastern and Western European IBD patients. Methods: The EpiCom cohort is a population-based, prospective inception cohort of 1560 unselected IBD patients from 31 European countries covering a background population of 10.1. million. At the time of diagnosis patients were asked to complete an 87-item questionnaire concerning environmental factors. Results: A total of 1182 patients (76%) answered the questionnaire, 444 (38%) had Crohn's disease (CD), 627 (53%) ulcerative colitis (UC), and 111 (9%) IBD unclassified. No geographic differences regarding smoking status, caffeine intake, use of oral contraceptives, or number of first-degree relatives with IBD were found. Sugar intake was higher in CD and UC patients from Eastern Europe than in Western Europe while fibre intake was lower (p.

Original languageEnglish
Pages (from-to)607-616
Number of pages10
JournalJournal of Crohn's and Colitis
Volume8
Issue number7
DOIs
Publication statusPublished - Jul 1 2014

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Inflammatory Bowel Diseases
Eastern Europe
Population
Ulcerative Colitis
Crohn Disease
Environmental Exposure
Oral Contraceptives
Caffeine
Smoking
Incidence
Surveys and Questionnaires

Keywords

  • Environmental factors
  • Inception cohort
  • Inflammatory bowel disease
  • Population-based

ASJC Scopus subject areas

  • Gastroenterology
  • Medicine(all)

Cite this

Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study. / Burisch, J.; Pedersen, N.; Cukovic-Cavka, S.; Turk, N.; Kaimakliotis, I.; Duricova, D.; Bortlik, M.; Shonová, O.; Vind, I.; Avnstrøm, S.; Thorsgaard, N.; Krabbe, S.; Andersen, V.; Dahlerup, J. F.; Kjeldsen, J.; Salupere, R.; Olsen, J.; Nielsen, K. R.; Manninen, P.; Collin, P.; Katsanos, K. H.; Tsianos, E. V.; Ladefoged, K.; Lakatos, L.; Ragnarsson, G.; Björnsson, E.; Bailey, Y.; O'Morain, C.; Schwartz, D.; Odes, S.; Giannotta, M.; Girardin, G.; Kiudelis, G.; Kupcinskas, L.; Turcan, S.; Barros, L.; Magro, F.; Lazar, D.; Goldis, A.; Nikulina, I.; Belousova, E.; Martinez-Ares, D.; Hernandez, V.; Almer, S.; Zhulina, Y.; Halfvarson, J.; Arebi, N.; Tsai, H. H.; Sebastian, S.; Lakatos, P.; Langholz, E.; Munkholm, P.

In: Journal of Crohn's and Colitis, Vol. 8, No. 7, 01.07.2014, p. 607-616.

Research output: Contribution to journalArticle

Burisch, J, Pedersen, N, Cukovic-Cavka, S, Turk, N, Kaimakliotis, I, Duricova, D, Bortlik, M, Shonová, O, Vind, I, Avnstrøm, S, Thorsgaard, N, Krabbe, S, Andersen, V, Dahlerup, JF, Kjeldsen, J, Salupere, R, Olsen, J, Nielsen, KR, Manninen, P, Collin, P, Katsanos, KH, Tsianos, EV, Ladefoged, K, Lakatos, L, Ragnarsson, G, Björnsson, E, Bailey, Y, O'Morain, C, Schwartz, D, Odes, S, Giannotta, M, Girardin, G, Kiudelis, G, Kupcinskas, L, Turcan, S, Barros, L, Magro, F, Lazar, D, Goldis, A, Nikulina, I, Belousova, E, Martinez-Ares, D, Hernandez, V, Almer, S, Zhulina, Y, Halfvarson, J, Arebi, N, Tsai, HH, Sebastian, S, Lakatos, P, Langholz, E & Munkholm, P 2014, 'Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study', Journal of Crohn's and Colitis, vol. 8, no. 7, pp. 607-616. https://doi.org/10.1016/j.crohns.2013.11.021
Burisch, J. ; Pedersen, N. ; Cukovic-Cavka, S. ; Turk, N. ; Kaimakliotis, I. ; Duricova, D. ; Bortlik, M. ; Shonová, O. ; Vind, I. ; Avnstrøm, S. ; Thorsgaard, N. ; Krabbe, S. ; Andersen, V. ; Dahlerup, J. F. ; Kjeldsen, J. ; Salupere, R. ; Olsen, J. ; Nielsen, K. R. ; Manninen, P. ; Collin, P. ; Katsanos, K. H. ; Tsianos, E. V. ; Ladefoged, K. ; Lakatos, L. ; Ragnarsson, G. ; Björnsson, E. ; Bailey, Y. ; O'Morain, C. ; Schwartz, D. ; Odes, S. ; Giannotta, M. ; Girardin, G. ; Kiudelis, G. ; Kupcinskas, L. ; Turcan, S. ; Barros, L. ; Magro, F. ; Lazar, D. ; Goldis, A. ; Nikulina, I. ; Belousova, E. ; Martinez-Ares, D. ; Hernandez, V. ; Almer, S. ; Zhulina, Y. ; Halfvarson, J. ; Arebi, N. ; Tsai, H. H. ; Sebastian, S. ; Lakatos, P. ; Langholz, E. ; Munkholm, P. / Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study. In: Journal of Crohn's and Colitis. 2014 ; Vol. 8, No. 7. pp. 607-616.
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T1 - Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study

AU - Burisch, J.

AU - Pedersen, N.

AU - Cukovic-Cavka, S.

AU - Turk, N.

AU - Kaimakliotis, I.

AU - Duricova, D.

AU - Bortlik, M.

AU - Shonová, O.

AU - Vind, I.

AU - Avnstrøm, S.

AU - Thorsgaard, N.

AU - Krabbe, S.

AU - Andersen, V.

AU - Dahlerup, J. F.

AU - Kjeldsen, J.

AU - Salupere, R.

AU - Olsen, J.

AU - Nielsen, K. R.

AU - Manninen, P.

AU - Collin, P.

AU - Katsanos, K. H.

AU - Tsianos, E. V.

AU - Ladefoged, K.

AU - Lakatos, L.

AU - Ragnarsson, G.

AU - Björnsson, E.

AU - Bailey, Y.

AU - O'Morain, C.

AU - Schwartz, D.

AU - Odes, S.

AU - Giannotta, M.

AU - Girardin, G.

AU - Kiudelis, G.

AU - Kupcinskas, L.

AU - Turcan, S.

AU - Barros, L.

AU - Magro, F.

AU - Lazar, D.

AU - Goldis, A.

AU - Nikulina, I.

AU - Belousova, E.

AU - Martinez-Ares, D.

AU - Hernandez, V.

AU - Almer, S.

AU - Zhulina, Y.

AU - Halfvarson, J.

AU - Arebi, N.

AU - Tsai, H. H.

AU - Sebastian, S.

AU - Lakatos, P.

AU - Langholz, E.

AU - Munkholm, P.

PY - 2014/7/1

Y1 - 2014/7/1

N2 - Background and Aims: The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe possibly due to changes in environmental factors towards a more "westernised" standard of living. The aim of this study was to investigate differences in exposure to environmental factors prior to diagnosis in Eastern and Western European IBD patients. Methods: The EpiCom cohort is a population-based, prospective inception cohort of 1560 unselected IBD patients from 31 European countries covering a background population of 10.1. million. At the time of diagnosis patients were asked to complete an 87-item questionnaire concerning environmental factors. Results: A total of 1182 patients (76%) answered the questionnaire, 444 (38%) had Crohn's disease (CD), 627 (53%) ulcerative colitis (UC), and 111 (9%) IBD unclassified. No geographic differences regarding smoking status, caffeine intake, use of oral contraceptives, or number of first-degree relatives with IBD were found. Sugar intake was higher in CD and UC patients from Eastern Europe than in Western Europe while fibre intake was lower (p.

AB - Background and Aims: The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe possibly due to changes in environmental factors towards a more "westernised" standard of living. The aim of this study was to investigate differences in exposure to environmental factors prior to diagnosis in Eastern and Western European IBD patients. Methods: The EpiCom cohort is a population-based, prospective inception cohort of 1560 unselected IBD patients from 31 European countries covering a background population of 10.1. million. At the time of diagnosis patients were asked to complete an 87-item questionnaire concerning environmental factors. Results: A total of 1182 patients (76%) answered the questionnaire, 444 (38%) had Crohn's disease (CD), 627 (53%) ulcerative colitis (UC), and 111 (9%) IBD unclassified. No geographic differences regarding smoking status, caffeine intake, use of oral contraceptives, or number of first-degree relatives with IBD were found. Sugar intake was higher in CD and UC patients from Eastern Europe than in Western Europe while fibre intake was lower (p.

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