Engineering a biomimetic environment to pre-condition stem cells for efficacious cardiovascular repair

Aparna R. Chakravarti, Settimio Pacelli, Perwez Alam, Samik Bagchi, Saman Modaresi, A. Czirók, Rafeeq P.H. Ahmed, Arghya Paul

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Statement of Purpose: Myocardial infarction (MI) is amongst the main causes of mortality worldwide, affecting people across a wide range of ages. Stem cell-based therapies are a viable approach to repair cardiovascular tissues due to their advantageous effect in promoting angiogenesis and decreasing scar tissue development. But, their translation to the clinic is hindered by their lack of ability to secrete sufficient therapeutic factors and poor differentiation in vivo. To combat this problem, various strategies like genetic modification and biophysical pre-conditioning have aimed at enhancing the efficacy of stem cells for cardiovascular tissue regeneration.

Original languageEnglish
Title of host publicationSociety for Biomaterials Annual Meeting and Exposition 2019
Subtitle of host publicationThe Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
PublisherSociety for Biomaterials
Number of pages1
ISBN (Electronic)9781510883901
Publication statusPublished - Jan 1 2019
Event42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States
Duration: Apr 3 2019Apr 6 2019

Publication series

NameTransactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume40
ISSN (Print)1526-7547

Conference

Conference42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
CountryUnited States
CitySeattle
Period4/3/194/6/19

Fingerprint

Biomimetics
Stem cells
Repair
Stem Cells
Tissue
Tissue regeneration
Cell- and Tissue-Based Therapy
Cicatrix
Regeneration
Myocardial Infarction
Mortality
Therapeutics

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Biotechnology
  • Biomaterials
  • Materials Chemistry

Cite this

Chakravarti, A. R., Pacelli, S., Alam, P., Bagchi, S., Modaresi, S., Czirók, A., ... Paul, A. (2019). Engineering a biomimetic environment to pre-condition stem cells for efficacious cardiovascular repair. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40). Society for Biomaterials.

Engineering a biomimetic environment to pre-condition stem cells for efficacious cardiovascular repair. / Chakravarti, Aparna R.; Pacelli, Settimio; Alam, Perwez; Bagchi, Samik; Modaresi, Saman; Czirók, A.; Ahmed, Rafeeq P.H.; Paul, Arghya.

Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 2019. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Chakravarti, AR, Pacelli, S, Alam, P, Bagchi, S, Modaresi, S, Czirók, A, Ahmed, RPH & Paul, A 2019, Engineering a biomimetic environment to pre-condition stem cells for efficacious cardiovascular repair. in Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium, vol. 40, Society for Biomaterials, 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence, Seattle, United States, 4/3/19.
Chakravarti AR, Pacelli S, Alam P, Bagchi S, Modaresi S, Czirók A et al. Engineering a biomimetic environment to pre-condition stem cells for efficacious cardiovascular repair. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials. 2019. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium).
Chakravarti, Aparna R. ; Pacelli, Settimio ; Alam, Perwez ; Bagchi, Samik ; Modaresi, Saman ; Czirók, A. ; Ahmed, Rafeeq P.H. ; Paul, Arghya. / Engineering a biomimetic environment to pre-condition stem cells for efficacious cardiovascular repair. Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 2019. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium).
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