Endotoxin sensitivity of inbred mouse strains

S. I. Vas, R. S. Roy, H. G. Robson

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Inbred mouse strains show characteristic susceptibility to S. typhimurium infections. The sensitivity of the same strains to endotoxin is not parallel. While C3H/He J and C57Bl/6J mice were highly susceptible to infection they showed more resistance to purified endotoxin than A/J, a mouse strain relatively resistant to infection. These findings suggest that the death of mice during S. typhimurium infection is not due only to toxic effects of its lipopolysaccharide.

Original languageEnglish
Pages (from-to)767-769
Number of pages3
JournalCanadian journal of microbiology
Volume19
Issue number7
DOIs
Publication statusPublished - Jan 1 1973

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Genetics

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