Endogenous scavenger levels (vitamin E and A) of patients with chronic alcoholic liver disease under different environmental conditions.

T. Horváth, L. Szabó, Z. Nagy, A. Blázovics, K. Gergely, T. Schwarcz

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Serum level of endogenous scavengers (E and A vitamin) was studied in groups of patients with various chronic alcoholic liver diseases and in a healthy control group on polluted and non-polluted areas. Vitamin levels in patients with chronic liver disease are diminished in comparison to the healthy in general, but mainly in the cirrhotic group. Diminution of vitamin E levels was observed in earlier phase of liver disease than that of vitamin A levels. Patients and healthy control on polluted area showed more expressed diminution of vitamin levels than the same groups on non-polluted area. Free radical parameter (RBC diene conjugate content) and characteristic alcoholic parameters (serum GOT, gamma-GT, cholesterol level and liver GOT, gamma-GT content in biopsy specimen) were used to explain the differences between the same investigated groups on polluted and non-polluted areas. As conclusion can be supposed that industrial pollution of environment has a worsening effect in diseases with free radical mechanism.

Original languageEnglish
Pages (from-to)381-389
Number of pages9
JournalActa physiologica Hungarica
Volume80
Issue number1-4
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Physiology (medical)

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