Endocrine aspects in pathogenesis of mastitis in postpartum dairy cows

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

In well-managed dairy herds some environmental pathogens including Gram-negative (GN) strains (E. coli and others) have been recognized recently as the predominant causative microbes of mastitis in the peri-parturient period. In early weeks of lactation hyperketonaemia may predispose the high-producing cows for GN mastitis. In GN mastitis cytokines, eicosanoids and oxygen radicals are released, which are responsible for the local and systemic symptoms. Experimental administration of endotoxin induces a complex endocrine cascade. Similar changes in plasma levels of cortisol, insulin, insulin-like growth factor-I and thyroid hormones are seen also in severe cases of GN mastitis. However, leptin is not responsible for the anorexia associated with severe mastitis in ruminants. Mastitis can postpone the resumption of ovarian cyclic activity in dairy cows when its outbreak occurs between days 15 and 28 after calving (at the expected time of first ovulation). In cyclic cows severe cases of GN mastitis can induce premature luteolysis or prolong the follicular phase.

Original languageEnglish
Pages (from-to)389-400
Number of pages12
JournalAnimal Reproduction Science
Volume82-83
DOIs
Publication statusPublished - Jul 2004

Fingerprint

Mastitis
Postpartum Period
mastitis
pathogenesis
dairy cows
hyperketonemia
Luteolysis
cows
luteolysis
Follicular Phase
eicosanoids
Eicosanoids
Ruminants
Anorexia
endotoxins
early lactation
thyroid hormones
insulin-like growth factor I
Leptin
Ovulation

Keywords

  • Dairy cow
  • Hormone
  • Mastitis
  • Ovary
  • Postpartum period

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Biotechnology
  • Genetics

Cite this

Endocrine aspects in pathogenesis of mastitis in postpartum dairy cows. / Huszenicza, G.; Jánosi, S.; Gáspárdy, A.; Kulcsár, M.

In: Animal Reproduction Science, Vol. 82-83, 07.2004, p. 389-400.

Research output: Contribution to journalArticle

@article{d1f14eed316245b0a2795a4ef08cb22b,
title = "Endocrine aspects in pathogenesis of mastitis in postpartum dairy cows",
abstract = "In well-managed dairy herds some environmental pathogens including Gram-negative (GN) strains (E. coli and others) have been recognized recently as the predominant causative microbes of mastitis in the peri-parturient period. In early weeks of lactation hyperketonaemia may predispose the high-producing cows for GN mastitis. In GN mastitis cytokines, eicosanoids and oxygen radicals are released, which are responsible for the local and systemic symptoms. Experimental administration of endotoxin induces a complex endocrine cascade. Similar changes in plasma levels of cortisol, insulin, insulin-like growth factor-I and thyroid hormones are seen also in severe cases of GN mastitis. However, leptin is not responsible for the anorexia associated with severe mastitis in ruminants. Mastitis can postpone the resumption of ovarian cyclic activity in dairy cows when its outbreak occurs between days 15 and 28 after calving (at the expected time of first ovulation). In cyclic cows severe cases of GN mastitis can induce premature luteolysis or prolong the follicular phase.",
keywords = "Dairy cow, Hormone, Mastitis, Ovary, Postpartum period",
author = "G. Huszenicza and S. J{\'a}nosi and A. G{\'a}sp{\'a}rdy and M. Kulcs{\'a}r",
year = "2004",
month = "7",
doi = "10.1016/j.anireprosci.2004.04.029",
language = "English",
volume = "82-83",
pages = "389--400",
journal = "Animal Reproduction Science",
issn = "0378-4320",
publisher = "Elsevier",

}

TY - JOUR

T1 - Endocrine aspects in pathogenesis of mastitis in postpartum dairy cows

AU - Huszenicza, G.

AU - Jánosi, S.

AU - Gáspárdy, A.

AU - Kulcsár, M.

PY - 2004/7

Y1 - 2004/7

N2 - In well-managed dairy herds some environmental pathogens including Gram-negative (GN) strains (E. coli and others) have been recognized recently as the predominant causative microbes of mastitis in the peri-parturient period. In early weeks of lactation hyperketonaemia may predispose the high-producing cows for GN mastitis. In GN mastitis cytokines, eicosanoids and oxygen radicals are released, which are responsible for the local and systemic symptoms. Experimental administration of endotoxin induces a complex endocrine cascade. Similar changes in plasma levels of cortisol, insulin, insulin-like growth factor-I and thyroid hormones are seen also in severe cases of GN mastitis. However, leptin is not responsible for the anorexia associated with severe mastitis in ruminants. Mastitis can postpone the resumption of ovarian cyclic activity in dairy cows when its outbreak occurs between days 15 and 28 after calving (at the expected time of first ovulation). In cyclic cows severe cases of GN mastitis can induce premature luteolysis or prolong the follicular phase.

AB - In well-managed dairy herds some environmental pathogens including Gram-negative (GN) strains (E. coli and others) have been recognized recently as the predominant causative microbes of mastitis in the peri-parturient period. In early weeks of lactation hyperketonaemia may predispose the high-producing cows for GN mastitis. In GN mastitis cytokines, eicosanoids and oxygen radicals are released, which are responsible for the local and systemic symptoms. Experimental administration of endotoxin induces a complex endocrine cascade. Similar changes in plasma levels of cortisol, insulin, insulin-like growth factor-I and thyroid hormones are seen also in severe cases of GN mastitis. However, leptin is not responsible for the anorexia associated with severe mastitis in ruminants. Mastitis can postpone the resumption of ovarian cyclic activity in dairy cows when its outbreak occurs between days 15 and 28 after calving (at the expected time of first ovulation). In cyclic cows severe cases of GN mastitis can induce premature luteolysis or prolong the follicular phase.

KW - Dairy cow

KW - Hormone

KW - Mastitis

KW - Ovary

KW - Postpartum period

UR - http://www.scopus.com/inward/record.url?scp=3543052967&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3543052967&partnerID=8YFLogxK

U2 - 10.1016/j.anireprosci.2004.04.029

DO - 10.1016/j.anireprosci.2004.04.029

M3 - Article

VL - 82-83

SP - 389

EP - 400

JO - Animal Reproduction Science

JF - Animal Reproduction Science

SN - 0378-4320

ER -