Enantioselective reduction of prochiral ketones by chromium(II) complexes with amino acid ligands as the source of chirality

T. Patonay, C. Hajdu, J. Jekó́, A. Lévai, K. Micskei, C. Zucchi

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Prochiral ketones were reduced to enantiomerically enriched secondary alcohols by Cr(II)[L-amino acid] complexes in good yields and moderate enantioselectivity.

Original languageEnglish
Pages (from-to)1373-1374
Number of pages2
JournalTetrahedron Letters
Volume40
Issue number7
DOIs
Publication statusPublished - Feb 12 1999

Fingerprint

Chirality
Enantioselectivity
Chromium
Ketones
Alcohols
Ligands
Amino Acids

Keywords

  • Amino acids
  • Chromans
  • Ketones
  • Reduction

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

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title = "Enantioselective reduction of prochiral ketones by chromium(II) complexes with amino acid ligands as the source of chirality",
abstract = "Prochiral ketones were reduced to enantiomerically enriched secondary alcohols by Cr(II)[L-amino acid] complexes in good yields and moderate enantioselectivity.",
keywords = "Amino acids, Chromans, Ketones, Reduction",
author = "T. Patonay and C. Hajdu and J. Jek{\'o}́ and A. L{\'e}vai and K. Micskei and C. Zucchi",
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T1 - Enantioselective reduction of prochiral ketones by chromium(II) complexes with amino acid ligands as the source of chirality

AU - Patonay, T.

AU - Hajdu, C.

AU - Jekó́, J.

AU - Lévai, A.

AU - Micskei, K.

AU - Zucchi, C.

PY - 1999/2/12

Y1 - 1999/2/12

N2 - Prochiral ketones were reduced to enantiomerically enriched secondary alcohols by Cr(II)[L-amino acid] complexes in good yields and moderate enantioselectivity.

AB - Prochiral ketones were reduced to enantiomerically enriched secondary alcohols by Cr(II)[L-amino acid] complexes in good yields and moderate enantioselectivity.

KW - Amino acids

KW - Chromans

KW - Ketones

KW - Reduction

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