Enantioselective reduction of C=N double bond by chromium(II) complexes of natural amino acids

K. Micskei, Orsolya Holczknecht, Valér Marchis, A. Lévai, T. Patonay, Claudia Zucchi, Gyula Pályi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Asymmetric reduction of oximes was performed by chromium(II) complexes of natural amino acids in aqueous phase or in H2O/DMF (1:1) solvent. Medium-to-quantitative chemoselectivity (54% to >95%) and low-to-medium enantioselectivity (5-50% ee) were found.

Original languageEnglish
Pages (from-to)511-514
Number of pages4
JournalChirality
Volume17
Issue number9
DOIs
Publication statusPublished - 2005

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Oximes
Enantioselectivity
Chromium
Amino acids
Amino Acids
1-deoxy-1-morpholinofructose

Keywords

  • Amino acid ligands
  • Asymmetric induction
  • Chromium(II) complexes
  • Oxime reduction
  • Reduction

ASJC Scopus subject areas

  • Analytical Chemistry
  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

Cite this

Enantioselective reduction of C=N double bond by chromium(II) complexes of natural amino acids. / Micskei, K.; Holczknecht, Orsolya; Marchis, Valér; Lévai, A.; Patonay, T.; Zucchi, Claudia; Pályi, Gyula.

In: Chirality, Vol. 17, No. 9, 2005, p. 511-514.

Research output: Contribution to journalArticle

Micskei, K. ; Holczknecht, Orsolya ; Marchis, Valér ; Lévai, A. ; Patonay, T. ; Zucchi, Claudia ; Pályi, Gyula. / Enantioselective reduction of C=N double bond by chromium(II) complexes of natural amino acids. In: Chirality. 2005 ; Vol. 17, No. 9. pp. 511-514.
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