Enantioselective reduction of C=N double bond by chromium(II) complexes of natural amino acids

Károly Micskei, Orsolya Holczknecht, Valér Marchis, Albert Lévai, Tamás Patonay, Claudia Zucchi, Gyula Pályi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Asymmetric reduction of oximes was performed by chromium(II) complexes of natural amino acids in aqueous phase or in H2O/DMF (1:1) solvent. Medium-to-quantitative chemoselectivity (54% to >95%) and low-to-medium enantioselectivity (5-50% ee) were found.

Original languageEnglish
Pages (from-to)511-514
Number of pages4
JournalChirality
Volume17
Issue number9
DOIs
Publication statusPublished - Nov 7 2005

Keywords

  • Amino acid ligands
  • Asymmetric induction
  • Chromium(II) complexes
  • Oxime reduction
  • Reduction

ASJC Scopus subject areas

  • Analytical Chemistry
  • Catalysis
  • Pharmacology
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry

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