Enantiomeric separation of 2-chloropropionic acid by enzymatic esterification in organic solvents

J. Bodnár, L. Gubicza, L. P. Szabó

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The kinetic resolution of 2-chloro-propionic acid by enzyme catalyzed esterification in different organic solvents has been studied. The rate and enantioselectivity of the reaction catalyzed by yeast (Canadida cylindracea) lipase were determined under various reaction conditions. The effect of several reaction parameters, such as solvent polarity, water content of the reaction mixture, the nature of the nucleophilic agent, the molar ratio of the substrates and the reaction temperature, are discussed.

Original languageEnglish
Pages (from-to)353-361
Number of pages9
JournalJournal of Molecular Catalysis
Volume61
Issue number3
DOIs
Publication statusPublished - Sep 1 1990

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Enzyme kinetics
Propionic acid
Enantioselectivity
Lipases
Esterification
Yeast
Organic solvents
Water content
Enzymes
Acids
Substrates
Temperature

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Enantiomeric separation of 2-chloropropionic acid by enzymatic esterification in organic solvents. / Bodnár, J.; Gubicza, L.; Szabó, L. P.

In: Journal of Molecular Catalysis, Vol. 61, No. 3, 01.09.1990, p. 353-361.

Research output: Contribution to journalArticle

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